Early-life stress, HPA axis adaptation, and mechanisms contributing to later health outcomes
Stress activates the hypothalamic–pituitary–adrenal (HPA) axis, which then modulates the
degree of adaptation and response to a later stressor. It is known that early-life stress can …
degree of adaptation and response to a later stressor. It is known that early-life stress can …
Glucocorticoid-induced fatty liver disease
Glucocorticoids (GCs) are commonly used at high doses and for prolonged periods (weeks
to months) in the treatment of a variety of diseases. Among the many side effects are …
to months) in the treatment of a variety of diseases. Among the many side effects are …
Glucocorticoids and non-alcoholic fatty liver disease
CP Woods, JM Hazlehurst, JW Tomlinson - The Journal of steroid …, 2015 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the global obesity
and metabolic disease epidemic and is rapidly becoming the leading cause of liver cirrhosis …
and metabolic disease epidemic and is rapidly becoming the leading cause of liver cirrhosis …
[HTML][HTML] Role of nonalcoholic fatty liver disease as risk factor for drug-induced hepatotoxicity
J Massart, K Begriche, C Moreau… - Journal of clinical and …, 2017 - ncbi.nlm.nih.gov
Background: Obesity is often associated with nonalcoholic fatty liver disease (NAFLD),
which refers to a large spectrum of hepatic lesions including fatty liver, nonalcoholic …
which refers to a large spectrum of hepatic lesions including fatty liver, nonalcoholic …
Mechanisms in endocrinology: local and systemic effects of glucocorticoids on metabolism: new lessons from animal models
M Swarbrick, H Zhou, M Seibel - European journal of …, 2021 - academic.oup.com
Glucocorticoids regulate a remarkable variety of essential functions, including development,
immunomodulation, maintenance of circadian rhythm and the response to stress …
immunomodulation, maintenance of circadian rhythm and the response to stress …
Drug-induced liver injury in obesity and nonalcoholic fatty liver disease
J Allard, D Le Guillou, K Begriche… - Advances in Pharmacology, 2019 - Elsevier
Obesity is commonly associated with nonalcoholic fatty liver (NAFL), a benign condition
characterized by hepatic lipid accumulation. However, NAFL can progress in some patients …
characterized by hepatic lipid accumulation. However, NAFL can progress in some patients …
[HTML][HTML] Relationship between diet and non-alcoholic fatty liver disease: a review article
P Mirmiran, Z Amirhamidi, HS Ejtahed… - Iranian journal of …, 2017 - ncbi.nlm.nih.gov
Background: Diet plays a key role in the development of non-alcoholic fatty liver disease
(NAFLD). The aim of this study was to review systematically observational studies available …
(NAFLD). The aim of this study was to review systematically observational studies available …
Role of steroid hormones in the pathogenesis of nonalcoholic fatty liver disease
M Yang, F Ma, M Guan - Metabolites, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
and may progress to cirrhosis or even hepatocellular carcinoma. A number of steroid …
and may progress to cirrhosis or even hepatocellular carcinoma. A number of steroid …
[HTML][HTML] Co-existence of non-alcoholic fatty liver disease and inflammatory bowel disease: A review article
CY Chao, R Battat, A Al Khoury… - World journal of …, 2016 - ncbi.nlm.nih.gov
Emerging data have highlighted the co-existence of non-alcoholic fatty liver disease
(NAFLD) and inflammatory bowel disease; both of which are increasingly prevalent …
(NAFLD) and inflammatory bowel disease; both of which are increasingly prevalent …
[HTML][HTML] Microbiome-liver crosstalk: A multihit therapeutic target for liver disease
J Kirundi, S Moghadamrad… - World journal of …, 2023 - ncbi.nlm.nih.gov
Liver disease has become a leading cause of death, particularly in the West, where it is
attributed to more than two million deaths annually. The correlation between gut microbiota …
attributed to more than two million deaths annually. The correlation between gut microbiota …