Nonhealing diabetic foot ulcers (DFUs) are a continuing clinical issue despite the improved
treatment with wound debridement, off-loading the ulcer, medication, wound dressings, and …

Diabetic wounds often have a slow healing process and become easily infected owing to
hyperglycemia in wound beds. Once planktonic bacterial cells develop into biofilms, the …

Chronic diabetic wounds are a significant global healthcare challenge. Current strategies,
such as biomaterials, cell therapies, and medical devices, however, only target a few …

Extracellular vesicles (EVs) derived from mesenchymal stem cells isolated from both bone
marrow (BMSCs) and adipose tissue (ADSCs) show potential therapeutic effects. These …

Among the numerous types of chronic skin wounds, the treatment of diabetic foot ulcers
(DFU) remains a major challenge, in view of its etiology. The high rates of amputation even …

Diabetic wounds are one of the debilitating complications that affect up to 20% of diabetic
patients. Despite the advent of extensive therapies, the recovery rate is unsatisfactory, and …

Chronic wounds represent a major challenge to the present healthcare system. In recent
decades, many topical therapies have been investigated for the treatment of chronic …

Diabetic wounds are among the major healthcare challenges, consuming billions of dollars
of resources and resulting in high numbers of morbidity and mortality every year. Lack of …

The healing process at a wound is made up of many types of cells, growth factors, the
extracellular matrix, nerves and blood vessels all interacting with each other in complex and …

Monocytes (Mo) and macrophages (Mϕ) play important roles in normal skin wound healing,
and dysregulation of wound Mo/Mϕ leads to impaired wound healing in diabetes. Although …