The arachidonic acid (AA) pathway plays a key role in cardiovascular biology,
carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified …

Lipid and immune pathways are crucial in the pathophysiology of metabolic and
cardiovascular disease. Arachidonic acid (AA) and its derivatives link nutrient metabolism to …

Arachidonic acid (AA), an n‐6 essential fatty acid, is a major component of mammalian cells
and can be released by phospholipase A2. Accumulating evidence indicates that AA plays …

Leukotrienes, a class of arachidonic acid–derived bioactive molecules, are known as
mediators of allergic and inflammatory reactions and considered to be important drug …

Acute coronary syndrome (ACS) is a set of signs and symptoms caused by a reduction of
coronary blood flow with subsequent myocardial ischemia. ACS is associated with activation …

Importance The evidence base for the association between montelukast and adverse
neuropsychiatric outcomes is mixed and inconclusive. Several methodological limitations …

Cysteinyl leukotrienes (CysLTs) are potent lipid inflammatory mediators synthesized from
arachidonic acid, through the 5‐lipoxygenase (5‐LO) pathway. Owing to their properties …

Arachidonic acid is metabolized by cyclooxygenase, lipoxygenase, and cytochrome P450
enzymes to produce prostaglandins, leukotrienes, epoxyeicosatrienoic acids (EETs), and …

It is commonly believed that the inactivation of inflammation is mainly due to the decay or
cessation of inducers. In reality, in connection with the development of atherosclerosis …

Chronic inflammation and pain is a major global health problem, and nonsteroidal anti-
inflammatory drugs (NSAIDs) remain the most frequently prescribed drugs and common …