[HTML][HTML] FOXM1: an emerging master regulator of DNA damage response and genotoxic agent resistance

S Zona, L Bella, MJ Burton, GN de Moraes… - Biochimica Et Biophysica …, 2014 - Elsevier
FOXM1 is a transcription factor required for a wide spectrum of essential biological functions,
including DNA damage repair, cell proliferation, cell cycle progression, cell renewal, cell …

Mitotic slippage: an old tale with a new twist

D Sinha, PHG Duijf, KK Khanna - Cell cycle, 2019 - Taylor & Francis
Targeting the mitotic machinery using anti-mitotic drugs for elimination of cancer cells is a
century-old concept, which continues to be routinely used as a first line of treatment in the …

[HTML][HTML] EGLN1/c-Myc induced lymphoid-specific helicase inhibits ferroptosis through lipid metabolic gene expression changes

Y Jiang, C Mao, R Yang, B Yan, Y Shi, X Liu, W Lai… - Theranostics, 2017 - ncbi.nlm.nih.gov
Ferroptosis is a newly discovered form of non-apoptotic cell death in multiple human
diseases. However, the epigenetic mechanisms underlying ferroptosis remain poorly …

[HTML][HTML] Cell cycle regulation of human DNA repair and chromatin remodeling genes

R Mjelle, SA Hegre, PA Aas, G Slupphaug, F Drabløs… - DNA repair, 2015 - Elsevier
Maintenance of a genome requires DNA repair integrated with chromatin remodeling. We
have analyzed six transcriptome data sets and one data set on translational regulation of …

Identification of cell cycle–regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors

GD Grant, L Brooks 3rd, X Zhang… - Molecular biology of …, 2013 - Am Soc Cell Biol
We identify the cell cycle–regulated mRNA transcripts genome-wide in the osteosarcoma-
derived U2OS cell line. This results in 2140 transcripts mapping to 1871 unique cell cycle …

The transcription factor FOXM1 (Forkhead box M1): proliferation-specific expression, transcription factor function, target genes, mouse models, and normal biological …

I Wierstra - Advances in cancer research, 2013 - Elsevier
Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor,
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …

FOXM1 (Forkhead box M1) in tumorigenesis: overexpression in human cancer, implication in tumorigenesis, oncogenic functions, tumor-suppressive properties, and …

I Wierstra - Advances in cancer research, 2013 - Elsevier
Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor
and is also intimately involved in tumorigenesis. FOXM1 stimulates cell proliferation and cell …

Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesis

J Jeffery, D Sinha, S Srihari, M Kalimutho, KK Khanna - Oncogene, 2016 - nature.com
CEP55 was initially identified as a pivotal component of abscission, the final stage of
cytokinesis, serving to regulate the physical separation of two daughter cells. Over the past …

Transcriptome reprogramming by cancer exosomes: identification of novel molecular targets in matrix and immune modulation

F Qadir, MA Aziz, CP Sari, H Ma, H Dai, X Wang… - Molecular cancer, 2018 - Springer
Background Exosomes are extracellular vesicles released by almost all cell types, including
cancer cells, into bodily fluids such as saliva, plasma, breast milk, semen, urine …

SPAG5 interacts with CEP55 and exerts oncogenic activities via PI3K/AKT pathway in hepatocellular carcinoma

YF Yang, MF Zhang, QH Tian, J Fu, X Yang, CZ Zhang… - Molecular cancer, 2018 - Springer
Background Deregulation of microtubules and centrosome integrity is response for the
initiation and progression of human cancers. Sperm-associated antigen 5 (SPAG5) is …