Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention

CL Holmes, OR Albin, HLT Mobley… - Nature Reviews …, 2024 - nature.com
Bloodstream infections (BSIs) are common in hospitals, often life-threatening and increasing
in prevalence. Microorganisms in the blood are usually rapidly cleared by the immune …

Stenotrophomonas maltophilia Infections: A Systematic Review and Meta-Analysis of Comparative Efficacy of Available Treatments, with Critical Assessment of Novel …

AE Maraolo, F Licciardi, I Gentile, A Saracino, A Belati… - Antibiotics, 2023 - mdpi.com
Stenotrophomonas maltophilia (SM) represents a challenging pathogen due to its resistance
profile. A systematic review of the available evidence was conducted to evaluate the best …

Case report: Analysis of phage therapy failure in a patient with a Pseudomonas aeruginosa prosthetic vascular graft infection

L Blasco, I López-Hernández… - Frontiers in …, 2023 - frontiersin.org
Clinical case of a patient with a Pseudomonas aeruginosa multidrug-resistant prosthetic
vascular graft infection which was treated with a cocktail of phages (PT07, 14/01, and PNM) …

Duration of Treatment for Pseudomonas aeruginosa Bacteremia: a Retrospective Study

T Babich, P Naucler, JK Valik, CG Giske… - Infectious Diseases and …, 2022 - Springer
Introduction There is no consensus regarding optimal duration of antibiotic therapy for
Pseudomonas aeruginosa bacteremia. We aimed to evaluate the impact of short antibiotic …

How to Manage Pseudomonas aeruginosa Infections

M Papadimitriou-Olivgeris, D Jacot, B Guery - … : Biology, Pathogenesis and …, 2022 - Springer
Pseudomonas aeruginosa is a pathogen frequently encountered in healthcare-associated
infections and immunocompromised patients. In bacteremia, this pathogen is associated …

Beta-lactam monotherapy or combination therapy for bloodstream infections or pneumonia due to Pseudomonas aeruginosa: A meta-analysis

L Onorato, M Macera, F Calò, P Cirillo… - International Journal of …, 2022 - Elsevier
Objectives To compare the clinical and microbiological outcomes of patients treated with
beta-lactam monotherapy or combination therapy for Pseudomonas aeruginosa infections …

Intravenous fosfomycin in combination regimens as a treatment option for difficult-to-treat infections due to multi-drug-resistant Gram-negative organisms: A real-life …

M Meschiari, M Faltoni, S Kaleci, G Tassoni… - International Journal of …, 2024 - Elsevier
Aim To investigate the efficacy of intravenous (IV) fosfomycin as combination therapy for
treatment of difficult-to-treat (DTT) acute and subacute infections with multi-drug-resistant …

[HTML][HTML] Evidence-based treatment of Pseudomonas aeruginosa infections: a critical reappraisal

A Karruli, C Catalini, C D'Amore, F Foglia, F Mari… - Antibiotics, 2023 - mdpi.com
Multidrug-resistant (MDR)/extensively drug-resistant (XDR) Pseudomonas aeruginosa is
emerging as a major threat related to adverse patient outcomes. The goal of this review is to …

Combination Therapy with Ciprofloxacin and Pentamidine against Multidrug-Resistant Pseudomonas aeruginosa: Assessment of In Vitro and In Vivo Efficacy and the …

M Fletcher, A McCormack, BJ Parcell, PJ Coote - Antibiotics, 2023 - mdpi.com
The aim of this work was to (i) evaluate the efficacy of a combination treatment of
pentamidine with ciprofloxacin against Galleria mellonella larvae infected with an MDR …

The challenge of bacteremia treatment due to non-fermenting gram-negative bacteria

S Sadyrbaeva-Dolgova, MM Sánchez-Suárez… - Microorganisms, 2023 - mdpi.com
Nosocomial infections caused by non-fermenting Gram-negative bacteria are a real
challenge for clinicians, especially concerning the accuracy of empirical treatment. This …