Obesity, type 2 diabetes, and cancer risk

T Scully, A Ettela, D LeRoith, EJ Gallagher - Frontiers in oncology, 2021 - frontiersin.org
Obesity and type 2 diabetes have both been associated with increased cancer risk and are
becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and …

Diabetes, obesity, and cancer—pathophysiology and clinical implications

IC Lega, LL Lipscombe - Endocrine reviews, 2020 - academic.oup.com
Obesity and diabetes have both been associated with an increased risk of cancer. In the
face of increasing obesity and diabetes rates worldwide, this is a worrying trend for cancer …

[HTML][HTML] Diabetes and cancer: Epidemiological and biological links

M Wang, Y Yang, Z Liao - World journal of diabetes, 2020 - ncbi.nlm.nih.gov
The incidence of diabetes and cancer has increased significantly in recent years.
Furthermore, there are many common risk factors for both diabetes and cancer, such as …

Association of metformin with breast cancer incidence and mortality in patients with type II diabetes: a GRADE-assessed systematic review and meta-analysis

GH Tang, M Satkunam, GR Pond, GR Steinberg… - … , biomarkers & prevention, 2018 - AACR
Background: Preclinical data suggest that metformin may reduce breast cancer incidence
and improve cancer prognosis. However, the current evidence in observational studies is …

The impact of diabetes on breast cancer treatments and outcomes: a population-based study

IC Lega, PC Austin, HD Fischer, K Fung… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE Women with breast cancer and diabetes face worse outcomes than those with
breast cancer without diabetes; however, the contribution of comorbidity to these disparities …

Associations between comorbidities and advanced stage diagnosis of lung, breast, colorectal, and prostate cancer: A systematic review and meta-analysis

D Boakye, K Günther, T Niedermaier, U Haug… - Cancer …, 2021 - Elsevier
Comorbidities and advanced stage diagnosis (ASD) are both associated with poorer cancer
outcomes, but the association between comorbidities and ASD is poorly understood. We …

Cancer and diabetes co-occurrence: A national study with 44 million person-years of follow-up

J Gurney, J Stanley, A Teng, J Krebs, J Koea, C Lao… - Plos one, 2022 - journals.plos.org
The number of new cases of cancer is increasing each year, and rates of diabetes mellitus
are also increasing dramatically over time. It is not an unusual occurrence for an individual …

Association between COPD and Stage of Lung Cancer Diagnosis: A Population-Based Study

SJ Butler, AV Louie, R Sutradhar, L Paszat, D Brooks… - Current …, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is associated with an increased risk of lung
cancer; however, the association between COPD and stage of lung cancer diagnosis is …

[HTML][HTML] Associations between Diabetes Mellitus and Selected Cancers

M Pliszka, L Szablewski - International Journal of Molecular Sciences, 2024 - mdpi.com
Cancer is one of the major causes of mortality and is the second leading cause of death.
Diabetes mellitus is a serious and growing problem worldwide, and its prevalence continues …

Impact of type 2 diabetes on complications after primary breast cancer surgery: Danish population-based cohort study

K Kjærgaard, J Wheler, L Dihge… - British Journal of …, 2024 - academic.oup.com
Background Knowledge is sparse on the impact of type 2 diabetes (T2D) on surgical
outcomes after breast cancer surgery. This study investigated the association between T2D …