Cataracts

YC Liu, M Wilkins, T Kim, B Malyugin, JS Mehta - The Lancet, 2017 - thelancet.com
An estimated 95 million people worldwide are affected by cataract. Cataract still remains the
leading cause of blindness in middle-income and low-income countries. With the …

Drug loading of polymer implants by supercritical CO2 assisted impregnation: A review

M Champeau, JM Thomassin, T Tassaing… - Journal of controlled …, 2015 - Elsevier
Drug loaded implants also called drug-eluting implants have proven their benefits over
simple implants. Among the developed manufacturing processes, the supercritical CO 2 …

Hydrogels in ophthalmic applications

S Kirchhof, AM Goepferich, FP Brandl - European Journal of Pharmaceutics …, 2015 - Elsevier
More and more people worldwide are affected by severe eye diseases eventually leading to
visual impairment or blindness. In most cases, the treatment involves the application of …

[HTML][HTML] Secondary outcomes of lens and cataract surgery: More than just “best-corrected visual acuity”

I Hecht, P Kanclerz, R Tuuminen - Progress in Retinal and Eye Research, 2023 - Elsevier
Most studies evaluating cataract surgery focus on the primary outcome of early, central, best-
corrected visual acuity. However, cataract surgery and intraocular lens (IOL) design have …

Polysaccharide-based hydrogels for medical devices, implants and tissue engineering: A review

D Sanjanwala, V Londhe, R Trivedi, S Bonde… - International Journal of …, 2023 - Elsevier
Hydrogels are highly biocompatible biomaterials composed of crosslinked three-
dimensional networks of hydrophilic polymers. Owing to their natural origin, polysaccharide …

Recent advances of intraocular lens materials and surface modification in cataract surgery

C Luo, H Wang, X Chen, J Xu, H Yin… - … in Bioengineering and …, 2022 - frontiersin.org
Advances in cataract surgery have increased the demand for intraocular lens (IOL)
materials. At present, the progress of IOL materials mainly contains further improving …

Rabbit models of ocular diseases: new relevance for classical approaches

EY Zernii, VE Baksheeva, EN Iomdina… - CNS & Neurological …, 2016 - ingentaconnect.com
Over 100 million individuals are affected by irreversible visual impairments and blindness
worldwide, while ocular diseases remain a challenging problem despite significant …

Therapeutic ophthalmic lenses: a review

N Toffoletto, B Saramago, AP Serro - Pharmaceutics, 2020 - mdpi.com
An increasing incidence of eye diseases has been registered in the last decades in
developed countries due to the ageing of population, changes in lifestyle, environmental …

Dual drug delivery from hydrophobic and hydrophilic intraocular lenses: in-vitro and in-vivo studies

A Topete, J Tang, X Ding, HP Filipe, JA Saraiva… - Journal of Controlled …, 2020 - Elsevier
Posterior capsule opacification (PCO) still remains the most frequent long term complication
after cataract surgery, while endophthalmitis is rare but severe and should be prevented at …

Novel silicone hydrogel based on PDMS and PEGMA for contact lens application

CH Lin, YH Yeh, WC Lin, MC Yang - Colloids and Surfaces B: Biointerfaces, 2014 - Elsevier
A silicone-based hydrogel was synthesized from poly (dimethylsiloxane) dialkanol (PDMS),
isophorone diisocyanate (IPDI), 2-hydroxyethyl methacrylate (HEMA) and poly (ethylene …