Natural hydrogel-based bio-inks for 3D bioprinting in tissue engineering: a review

A Fatimi, OV Okoro, D Podstawczyk, J Siminska-Stanny… - Gels, 2022 - mdpi.com
Three-dimensional (3D) printing is well acknowledged to constitute an important technology
in tissue engineering, largely due to the increasing global demand for organ replacement …

3D organ-on-a-chip: The convergence of microphysiological systems and organoids

LS Baptista, C Porrini, GS Kronemberger… - Frontiers in Cell and …, 2022 - frontiersin.org
Medicine today faces the combined challenge of an increasing number of untreatable
diseases and fewer drugs reaching the clinic. While pharmaceutical companies have …

Core–shell bioprinting of vascularized in vitro liver sinusoid models

R Taymour, NA Chicaiza-Cabezas, M Gelinsky… - …, 2022 - iopscience.iop.org
In vitro liver models allow the investigation of the cell behavior in disease conditions or in
response to changes in the microenvironment. A major challenge in liver tissue engineering …

Mitochondria as the target of hepatotoxicity and drug-induced liver injury: molecular mechanisms and detection methods

M Mihajlovic, M Vinken - International journal of molecular sciences, 2022 - mdpi.com
One of the major mechanisms of drug-induced liver injury includes mitochondrial
perturbation and dysfunction. This is not a surprise, given that mitochondria are essential …

From non-alcoholic fatty liver disease to liver cancer: microbiota and inflammation as key players

A Rodríguez-Lara, A Rueda-Robles, MJ Sáez-Lara… - Pathogens, 2023 - mdpi.com
It is estimated that 25% of the world's population has non-alcoholic fatty liver disease. This
disease can advance to a more severe form, non-alcoholic steatohepatitis (NASH), a …

Advancing 3D bioprinting through machine learning and artificial intelligence

S Ramesh, A Deep, A Tamayol, A Kamaraj, C Mahajan… - Bioprinting, 2024 - Elsevier
Abstract 3D bioprinting, a vital tool in tissue engineering, drug testing, and disease
modeling, is increasingly integrated with machine learning (ML) and artificial intelligence …

Application of 3D bioprinting in liver diseases

W Li, Z Liu, F Tang, H Jiang, Z Zhou, X Hao, JM Zhang - Micromachines, 2023 - mdpi.com
Liver diseases are the primary reason for morbidity and mortality in the world. Owing to a
shortage of organ donors and postoperative immune rejection, patients routinely suffer from …

Utilization of 3D bioprinting technology in creating human tissue and organoid models for preclinical drug research-state-of-the-art

J Frankowski, M Kurzątkowska, M Sobczak… - International Journal of …, 2023 - Elsevier
Rapid development of tissue engineering in recent years has increased the importance of
three-dimensional (3D) bioprinting technology as novel strategy for fabrication functional 3D …

[HTML][HTML] Could 3D extrusion bioprinting serve to be a real alternative to organ transplantation in the future?

K Shinkar, K Rhode - Annals of 3D Printed Medicine, 2022 - Elsevier
Additive manufacturing, or 3D printing, has made incredible steps over the last 30 years and
is now being widely used for healthcare applications. There has been increasing research …

[HTML][HTML] Emerging biotechnologies for engineering liver organoids

J Zhao, Y Zhi, H Ren, J Wang, Y Zhao - Bioactive Materials, 2025 - Elsevier
The engineering construction of the liver has attracted enormous attention. Organoids, as
emerging miniature three-dimensional cultivation units, hold significant potential in the …