Non-excitatory amino acids, melatonin, and free radicals: examining the role in stroke and aging
VJ Carretero, E Ramos, P Segura-Chama… - Antioxidants, 2023 - mdpi.com
The aim of this review is to explore the relationship between melatonin, free radicals, and
non-excitatory amino acids, and their role in stroke and aging. Melatonin has garnered …
non-excitatory amino acids, and their role in stroke and aging. Melatonin has garnered …
Melatonin treatment in kidney diseases
M Markowska, S Niemczyk, K Romejko - Cells, 2023 - mdpi.com
Melatonin is a neurohormone that is mainly secreted by the pineal gland. It coordinates the
work of the superior biological clock and consequently affects many processes in the human …
work of the superior biological clock and consequently affects many processes in the human …
Anti-inflammatory effects of melatonin in rats with induced type 2 diabetes mellitus
H Yapislar, E Haciosmanoglu, T Sarioglu… - Life, 2022 - mdpi.com
Introduction: Insulin resistance is associated with a pro-inflammatory state increasing the risk
for complications in patients with type 2 diabetes mellitus (T2DM). In addition to its …
for complications in patients with type 2 diabetes mellitus (T2DM). In addition to its …
Benefits of the neurogenic potential of melatonin for treating neurological and neuropsychiatric disorders
There are several neurological diseases under which processes related to adult brain
neurogenesis, such cell proliferation, neural differentiation and neuronal maturation, are …
neurogenesis, such cell proliferation, neural differentiation and neuronal maturation, are …
Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway
P Wang, S Zhang, S Lin, Z Lv - Reproductive Biology and Endocrinology, 2022 - Springer
Background Diabetes mellitus (DM)-related complications are important health problems
worldwide. The underlying mechanisms for diabetic male subfertility/infertility are …
worldwide. The underlying mechanisms for diabetic male subfertility/infertility are …
A novel therapeutic combination of sitagliptin and melatonin regenerates pancreatic β-cells in mouse and human islets
Autoimmune-led challenge resulting in β-cell loss is responsible for the development of type
1 diabetes (T1D). Melatonin, a pineal hormone or sitagliptin, a dipeptidyl peptidase IV (DPP …
1 diabetes (T1D). Melatonin, a pineal hormone or sitagliptin, a dipeptidyl peptidase IV (DPP …
Parkin-mediated mitophagy is negatively regulated by FOXO3A, which inhibits Plk3-mediated mitochondrial ROS generation in STZ diabetic stress-treated pancreatic …
JY Shim, JO Chung, D Jung, PS Kang, SY Park… - PloS one, 2023 - journals.plos.org
Diabetes mellitus (DM) is one of the most researched metabolic diseases worldwide. It leads
to extensive complications such as cardiovascular disease, nephropathy, retinopathy, and …
to extensive complications such as cardiovascular disease, nephropathy, retinopathy, and …
Hepatic encephalopathy and melatonin
A Arjunan, DK Sah, YD Jung, J Song - Antioxidants, 2022 - mdpi.com
Hepatic encephalopathy (HE) is a severe metabolic syndrome linked with acute/chronic
hepatic disorders. HE is also a pernicious neuropsychiatric complication associated with …
hepatic disorders. HE is also a pernicious neuropsychiatric complication associated with …
Melatonin attenuates cellular senescence and apoptosis in diabetic nephropathy by regulating STAT3 phosphorylation
X Fang, W Huang, Q Sun, Y Zhao, R Sun, F Liu… - Life Sciences, 2023 - Elsevier
Aims Melatonin is an endogenous hormone related to the regulation of biorhythm. Previous
researchers have found that melatonin can ameliorate diabetic nephropathy (DN), but the …
researchers have found that melatonin can ameliorate diabetic nephropathy (DN), but the …
[HTML][HTML] Effects of melatonin on glycemic variability in type 2 diabetes mellitus: Protocol for a crossover, double-blind, placebo-controlled trial
W Martorina, A Tavares - JMIR research protocols, 2023 - researchprotocols.org
Background: Glycemic variability is recognized as a significant factor contributing to the
development of micro-and macrovascular complications in individuals with type 2 diabetes …
development of micro-and macrovascular complications in individuals with type 2 diabetes …