[HTML][HTML] MicroRNAs and apoptosis in colorectal cancer
H Wang - International journal of molecular sciences, 2020 - mdpi.com
Colorectal cancer (CRC) is the third leading cause of cancer death in the world, and its
incidence is rising in developing countries. Treatment with 5-Fluorouracil (5-FU) is known to …
incidence is rising in developing countries. Treatment with 5-Fluorouracil (5-FU) is known to …
Crosstalk between TGF-β signaling and the microRNA machinery
H Butz, K Rácz, L Hunyady, A Patócs - Trends in pharmacological sciences, 2012 - cell.com
The activin/transforming growth factor-β (TGF-β) pathway plays an important role in
tumorigenesis either by its tumor suppressor or tumor promoting effect. Loss of members of …
tumorigenesis either by its tumor suppressor or tumor promoting effect. Loss of members of …
MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis
Q Xu, LZ Liu, X Qian, Q Chen, Y Jiang, D Li… - Nucleic acids …, 2012 - academic.oup.com
MiR-145 can regulate cell apoptosis, proliferation, neural development and stem cell
differentiation. Previous studies indicate that miR-145 is downregulated in human colon …
differentiation. Previous studies indicate that miR-145 is downregulated in human colon …
Salivary micro RNA s in oral cancer
F Zahran, D Ghalwash, O Shaker, K Al‐Johani… - Oral …, 2015 - Wiley Online Library
Objective This study investigated the use of three salivary micro RNA s (mi RNA‐21, mi RNA‐
184, and mi RNA‐145) as possible markers for malignant transformation in oral mucosal …
184, and mi RNA‐145) as possible markers for malignant transformation in oral mucosal …
Micro RNA‐145: a potent tumour suppressor that regulates multiple cellular pathways
SY Cui, R Wang, LB Chen - Journal of cellular and molecular …, 2014 - Wiley Online Library
Micro RNA s are endogenous, small (18–25 nucleotides) non‐coding RNA s, which regulate
genes expression by directly binding to the 3′‐untranslated regions of the target …
genes expression by directly binding to the 3′‐untranslated regions of the target …
Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop
Dysregulated microRNAs (miRNAs) have an important role in many malignant tumors.
However, elucidating the roles of miRNAs in cancer biology, especially in epithelial cancers …
However, elucidating the roles of miRNAs in cancer biology, especially in epithelial cancers …
[HTML][HTML] miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect
YAN Sun, X Zhao, Y Zhou, YU Hu - Oncology reports, 2012 - spandidos-publications.com
Colorectal cancer represents one of the most challenging diseases. Increasing evidence
indicates that aberrant expression of microRNAs (miRNAs) is related to pathogenesis of …
indicates that aberrant expression of microRNAs (miRNAs) is related to pathogenesis of …
MicroRNA in colorectal cancer: from benchtop to bedside
WKK Wu, PTY Law, CW Lee, CH Cho, D Fan… - …, 2011 - academic.oup.com
Colon carcinogenesis represents a stepwise progression from benign polyps to invasive
adenocarcinomas and distant metastasis. It is believed that these pathologic changes are …
adenocarcinomas and distant metastasis. It is believed that these pathologic changes are …
Function of microRNA-145 and mechanisms underlying its role in malignant tumor diagnosis and treatment
D Ye, Z Shen, S Zhou - Cancer management and research, 2019 - Taylor & Francis
miRNAs are single-stranded small RNAs that do not encode proteins. They can combine
complementarily with the 3′-UTRs of target gene mRNA molecules to promote targeted …
complementarily with the 3′-UTRs of target gene mRNA molecules to promote targeted …
miR‐145 sensitizes ovarian cancer cells to paclitaxel by targeting Sp1 and Cdk6
X Zhu, Y Li, C Xie, X Yin, Y Liu, Y Cao… - … journal of cancer, 2014 - Wiley Online Library
Multidrug resistance (MDR) remains a major obstacle to effective chemotherapy treatment in
ovarian cancer. In our study, paclitaxel‐resistant ovarian cancer patients and cell lines had …
ovarian cancer. In our study, paclitaxel‐resistant ovarian cancer patients and cell lines had …