Clinical and preclinical findings have suggested a role of the endocannabinoid system
(ECS) in the etiopathology of autism spectrum disorder (ASD). Previous mouse studies have …

Obesity is a multifactorial metabolic condition characterized by an abnormal or excessive
accumulation of fat in the adipose tissue, capable of decreasing life expectancy. Chronically …

Metabolic syndrome (MetS) is a complex disorder that stems from the additive effects of
multiple underlying causes such as obesity, insulin resistance, and chronic low-grade …

The Cannabinoid (CB) signalling cascade is widely located in the human body and is
associated with several pathophysiological processes. The endocannabinoid system …

Antagonists of peripheral type 1 cannabinoid receptors (CB1) may have utility in the
treatment of obesity, liver disease, metabolic syndrome and dyslipidemias. We have …

Mice emit ultrasonic vocalizations (USVs) to communicate each other in different social
conditions: pups maternal separation, juveniles play, adults mating and social investigation …

Cannabis use is on the rise leading to the need to address the medical, psychosocial, and
economic effects of cannabis intoxication. While effective agents have not yet been …

Every day, the questions about Cannabis sativa ability to cause chemical dependence are
closed with the considerable increase in the demand for treatment of addicts to this plant …