The association of the glymphatic function with Parkinson's disease symptoms: neuroimaging evidence from longitudinal and cross‐sectional studies

P He, L Shi, Y Li, Q Duan, Y Qiu, S Feng… - Annals of …, 2023 - Wiley Online Library
Objective Emerging pathological evidence suggests that there is an association between
glymphatic dysfunction and the progression of Parkinson's disease (PD). However, the …

Clinical and diagnostic implications of Alzheimer's disease copathology in Lewy body disease

L Barba, S Abu-Rumeileh, H Barthel, F Massa… - Brain, 2024 - academic.oup.com
Concomitant Alzheimer's disease (AD) pathology is a frequent event in the context of Lewy
body disease (LBD), occurring in approximately half of all cases. Evidence shows that LBD …

Radionuclide Imaging of the neuroanatomical and neurochemical substrate of Cognitive decline in Parkinson's Disease

S Booth, JH Ko - Nuclear Medicine and Molecular Imaging, 2024 - Springer
Cognitive impairment is a frequent manifestation of Parkinson's disease (PD), resulting in
decrease in patients' quality of life and increased societal and economic burden. However …

Associations of Alzheimer's-related plasma biomarkers with cognitive decline in Parkinson's disease

Y Mizutani, R Ohdake, H Tatebe, A Higashi… - Journal of …, 2023 - Springer
Background Parkinson's disease (PD) is associated with cognitive decline through multiple
mechanisms, including Alzheimer's disease (AD) pathology and cortical Lewy body …

Evolution and predictive role of plasma Alzheimer's disease-related pathological biomarkers in Parkinson's disease

J Lin, R Ou, C Li, Y Hou, L Zhang, Q Wei… - The Journals of …, 2023 - academic.oup.com
Plasma Alzheimer's disease-related pathological biomarkers' role in Parkinson's disease
(PD) remains unknown. We aimed to determine whether plasma Alzheimer's disease …

Characteristics of fatigue in Parkinson's disease: A longitudinal cohort study

X Zhou, Y Xiang, T Song, Y Zhao, H Pan… - Frontiers in Aging …, 2023 - frontiersin.org
Objective To assess the prevalence, evolution, clinical characteristics, correlates and
predictors of fatigue as well as to investigate the influence of comorbid fatigue on the …

CSF GPNMB in Parkinson's disease: A potential association with age and microglial activation

XC Zhu, Y Mizutani, R Ohdake… - Journal of …, 2024 - journals.sagepub.com
Background Recent evidence suggests a link between glycoprotein non-metastatic
melanoma protein B (GPNMB) and Parkinson's disease (PD) pathogenesis. Although …

Prevalence of concomitant pathologies in Parkinson's disease: Implications for prognosis, diagnosis, and insights into common pathogenic mechanisms

L Walker, J Attems - Journal of Parkinson's Disease, 2024 - content.iospress.com
Pathologies characteristic of Alzheimer's disease (ie, hyperphosphorylated tau and amyloid-
β (Aβ) plaques), cardiovascular disease, and limbic predominant TDP-43 encephalopathy …

[PDF][PDF] Neuroanatomical Signature of the Transition from Normal Cognition to MCI in Parkinson's Disease

I Beheshti, J Perron, JH Ko - Aging and Disease, 2025 - researchgate.net
The progression of Parkinson's disease (PD) is often accompanied by cognitive decline. We
had previously developed a brain age estimation program utilizing structural MRI data of …

The Role of Alpha-Synuclein and Tubulin-Associated Unit (Tau) Proteins in the Diagnosis, Prognosis, and Treatment of Parkinson's Disease: A Systematic Review

YM Lin, D Banoth, MH Wali, K Bekova, N Abdulla… - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Parkinson's disease (PD) is a degenerative neurological disorder resulting from the death of
dopaminergic neurons, which, in turn, results in impaired motor and cognitive functions …