Review of electroanalytical-based approaches for the determination of benzodiazepines

KC Honeychurch - Biosensors, 2019 - mdpi.com
The benzodiazepine class of drugs are characterised by a readily electrochemically
reducible azomethine group. A number are also substituted by other electrochemically …

Recent highlights on molecular hybrids potentially useful in central nervous system disorders

M Matias, S Silvestre, A Falcao… - Mini Reviews in …, 2017 - ingentaconnect.com
Molecular hybridization is a recent strategy based on the covalent fusion of two or more
pharmacophores to create a single molecule with multiple mechanisms of action, which …

Synthesis of Cu-porphyrazines by annulated diazepine rings with electrochemical, conductance activities and computational studies

AM Fahim, HS Magar, E Nasar, FM Abdelrazek… - Journal of Inorganic and …, 2022 - Springer
In this investigation, we synthesized novel Cu-porphyrazines annulated with diazepines
moiteis, the diazepines rings were obtained via 1, 4-cycloaddition reactions of chalcone …

Simplifying sample preparation using fabric phase sorptive extraction technique for the determination of benzodiazepines in blood serum by high‐performance liquid …

V Samanidou, I Kaltzi, A Kabir… - Biomedical …, 2016 - Wiley Online Library
Fabric phase sorptive extraction (FPSE), a recently introduced novel sample preparation
technology, has been evaluated for the extraction of benzodiazepines from human blood …

An ultra-sensitive UHPLC-QqQ-MS/MS method for determination of 54 benzodiazepines (pharmaceutical drugs, NPS and metabolites) and z-drugs in biological …

O Wachełko, P Szpot, K Tusiewicz, K Nowak… - Talanta, 2023 - Elsevier
Benzodiazepines exhibit central nervous system depressive activity as well as sedative,
hypnotic, and anticonvulsant properties, which enable to use them as medical treatment in …

Spectral trends in GC-EI-MS data obtained from the SWGDRUG mass spectral library and literature: A resource for the identification of unknown compounds

W Feeney, AS Moorthy, E Sisco - Forensic Chemistry, 2022 - Elsevier
Rapid identification of new or emerging psychoactive substances remains a critical
challenge in forensic drug chemistry laboratories. Current analytical protocols are well …

Rapid and simple multi-analyte LC–MS/MS method for the determination of benzodiazepines and Z-hypnotic drugs in blood samples: development, validation and …

L Banaszkiewicz, MK Woźniak, M Kata… - … of Pharmaceutical and …, 2020 - Elsevier
Benzodiazepines (BZDs) and Z-drugs have been particularly important treatments for
sleeping and anxiety disorders for many years. However, recently, a number of new …

The rapid measurement of benzodiazepines in a milk-based alcoholic beverage using QuEChERS extraction and GC–MS analysis

G Famiglini, F Capriotti, P Palma… - Journal of analytical …, 2015 - academic.oup.com
Benzodiazepines (BDZs) are widely used as tranquilizers and anti-depressive drugs in
common clinical practice. However, their ready availability and their synergistic effects with …

Development of a QuEChERS combined with LC-MS/MS method for determining 24 sedatives and anesthetics in animal-derived foods

M Wang, Y Qiao, Z Luo, E Guo, W Ma, K Wang… - Journal of Food …, 2024 - Elsevier
This study aims to establish a rapid, accurate, safe, inexpensive, and effective method that
combines QuEChERS pre-treatment with liquid chromatography-tandem mass spectrometry …

Analysis of benzodiazepines by thermal desorption direct analysis in real time mass spectrometry (TD-DART-MS)

S Jones, E Sisco, I Marginean - Analytical Methods, 2020 - pubs.rsc.org
One of the several classes of novel psychoactive substances (NPSs) that present analytical
challenges for forensic chemists is benzodiazepines. Like other NPS classes, the …