The Brain Endothelial Cell Glycocalyx Plays a Crucial Role in the Development of Enlarged Perivascular Spaces in Obesity, Metabolic Syndrome, and Type 2 …

MR Hayden - Life, 2023 - mdpi.com
The brain endothelial cell (BEC) glycocalyx (ecGCx) is a BEC surface coating consisting of a
complex interwoven polysaccharide (sweet husk) mesh-like network of membrane-bound …

Modifiable risk factors for brain health and dementia and opportunities for intervention: a brief review

DW Coon, A Gómez-Morales - Clinical Gerontologist, 2023 - Taylor & Francis
Maintaining brain health and promoting healthy lifestyle strategies to manage modifiable risk
factors is vital to ensuring well-being for all–not only for the individuals with memory …

Smoking is associated with impaired verbal learning and memory performance in women more than men

CR Lewis, JS Talboom, MD De Both, AM Schmidt… - Scientific reports, 2021 - nature.com
Vascular contributions to cognitive impairment and dementia (VCID) include structural and
functional blood vessel injuries linked to poor neurocognitive outcomes. Smoking might …

Protoplasmic Perivascular Astrocytes Play a Crucial Role in the Development of Enlarged Perivascular Spaces in Obesity, Metabolic Syndrome, and Type 2 Diabetes …

MR Hayden - Neuroglia, 2023 - mdpi.com
Astrocytes (ACs) are the most abundant cells in the brain and, importantly, are the master
connecting and communicating cells that provide structural and functional support for brain …

Neuroimaging and verbal memory assessment in healthy aging adults using a portable low-field MRI scanner and a web-based platform: results from a proof-of …

SCL Deoni, P Burton, J Beauchemin… - Brain Structure and …, 2023 - Springer
Consumer wearables and health monitors, internet-based health and cognitive
assessments, and at-home biosample (eg, saliva and capillary blood) collection kits are …

Remote, unsupervised functional motor task evaluation in older adults across the United States using the MindCrowd electronic cohort

A Hooyman, JS Talboom, MD DeBoth… - Developmental …, 2021 - Taylor & Francis
ABSTRACT COVID-19 has impacted the ability to evaluate motor function in older adults, as
motor assessments typically require face-to-face interaction. One hundred seventy-seven …

Establishing the Validity and Reliability of an Online Motor Learning Game: Applications for Alzheimer's Disease Research Within MindCrowd

A Hooyman, MJ Huentelman, M De Both… - Games for Health …, 2023 - liebertpub.com
Objective: Motor practice effects (ie, improvements in motor task performance with practice)
are emerging as a unique variable that can predict Alzheimer's disease (AD) progression …

Two separate, large cohorts reveal potential modifiers of age-associated variation in visual reaction time performance

JS Talboom, MD De Both, MA Naymik… - npj Aging and …, 2021 - nature.com
To identify potential factors influencing age-related cognitive decline and disease, we
created MindCrowd. MindCrowd is a cross-sectional web-based assessment of simple …

[HTML][HTML] Age and sex effects on Super G performance are consistent across internet devices

A Hooyman, SY Schaefer - International journal of serious games, 2023 - ncbi.nlm.nih.gov
There have been recent advances in the application of online games that assess motor skill
acquisition/learning and its relationship to age and biological sex, both of which are …

Increasing Hispanic Participation in Cognitive Research: An Examination of a Decade of Web-Based Recruitment into MindCrowd

T Nuño, KD Ellingson, Z Chen… - Hispanic Health …, 2024 - journals.sagepub.com
Introduction: The research community has struggled to successfully recruit and retain
Hispanic participants into research studies. The purpose of our study is to describe Hispanic …