Engineering biological nanopore approaches toward protein sequencing
Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …
protein studies, while the methods we have for identifying and quantifying individual proteins …
Conventional and nanotechnology-based sensing methods for SARS coronavirus (2019-nCoV)
Ongoing pandemic coronavirus (COVID-19) has affected over 218 countries and infected
88,512,243 and 1,906,853 deaths reported by Jan. 8, 2021. At present, vaccines are being …
88,512,243 and 1,906,853 deaths reported by Jan. 8, 2021. At present, vaccines are being …
A click chemistry amplified nanopore assay for ultrasensitive quantification of HIV-1 p24 antigen in clinical samples
Despite major advances in HIV testing, ultrasensitive detection of early infection remains
challenging, especially for the viral capsid protein p24, which is an early virological …
challenging, especially for the viral capsid protein p24, which is an early virological …
Multiplex quantitative detection of SARS-CoV-2 specific IgG and IgM antibodies based on DNA-assisted nanopore sensing
Abstract The coronavirus disease (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has spread into a global pandemic. Early and accurate …
coronavirus 2 (SARS-CoV-2) has spread into a global pandemic. Early and accurate …
Protein sequencing, one molecule at a time
BM Floyd, EM Marcotte - Annual review of biophysics, 2022 - annualreviews.org
Despite tremendous gains over the past decade, methods for characterizing proteins have
generally lagged behind those for nucleic acids, which are characterized by extremely high …
generally lagged behind those for nucleic acids, which are characterized by extremely high …
Narrowing Signal Distribution by Adamantane Derivatization for Amino Acid Identification Using an α-Hemolysin Nanopore
The rapid progress in nanopore sensing has sparked interest in protein sequencing. Despite
recent notable advancements in amino acid recognition using nanopores, chemical …
recent notable advancements in amino acid recognition using nanopores, chemical …
Recent advances in single-entity electrochemistry for metal nanoparticle, nanodroplet, and bio-entity analysis
JW Kim, G Aruchamy, BK Kim - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The field of analytical/electroanalytical chemistry has witnessed great improvements over
the past period. Single-entity electrochemistry (SEE) was developed approximately 20 years …
the past period. Single-entity electrochemistry (SEE) was developed approximately 20 years …
Is the volume exclusion model practicable for nanopore protein sequencing?
The nanopore approach holds the possibility for achieving single-molecule protein
sequencing. However, ongoing challenges still remain in the biological nanopore …
sequencing. However, ongoing challenges still remain in the biological nanopore …
Recent advances in biological nanopores for nanopore sequencing, sensing and comparison of functional variations in MspA mutants
H Bhatti, R Jawed, I Ali, K Iqbal, Y Han, Z Lu, Q Liu - Rsc Advances, 2021 - pubs.rsc.org
Biological nanopores are revolutionizing human health by the great myriad of detection and
diagnostic skills. Their nano-confined area and ingenious shape are suitable to investigate a …
diagnostic skills. Their nano-confined area and ingenious shape are suitable to investigate a …
Quantitation of Circulating Mycobacterium tuberculosis Antigens by Nanopore Biosensing in Children Evaluated for Pulmonary Tuberculosis in South Africa
Nanopore sensing of proteomic biomarkers lacks accuracy due to the ultralow abundance of
targets, a wide variety of interferents in clinical samples, and the mismatch between pore …
targets, a wide variety of interferents in clinical samples, and the mismatch between pore …