Plants as the extended phenotype of endophytes—the actual source of bioactive compounds

N Rutkowska, P Drożdżyński, M Ryngajłło… - International Journal of …, 2023 - mdpi.com
For thousands of years, plants have been used for their medicinal properties. The industrial
production of plant-beneficial compounds is facing many drawbacks, such as seasonal …

Lifestyle transitions in fusarioid fungi are frequent and lack clear genomic signatures

R Hill, RJA Buggs, DT Vu, E Gaya - Molecular Biology and …, 2022 - academic.oup.com
Abstract The fungal genus Fusarium (Ascomycota) includes well-known plant pathogens
that are implicated in diseases worldwide, and many of which have been genome …

The Sordariomycetes: an expanding resource with Big Data for mining in evolutionary genomics and transcriptomics

Z Wang, W Kim, YW Wang, E Yakubovich… - Frontiers in Fungal …, 2023 - frontiersin.org
Advances in genomics and transcriptomics accompanying the rapid accumulation of omics
data have provided new tools that have transformed and expanded the traditional concepts …

Global genome mining-driven discovery of an unusual biosynthetic logic for fungal polyketide–terpenoid hybrids

D Yan, Y Matsuda - Chemical Science, 2024 - pubs.rsc.org
Genome mining has facilitated the efficient discovery of untapped natural products. We
performed global genome mining in fungi and discovered a series of biosynthetic gene …

Endophyte genomes support greater metabolic gene cluster diversity compared with non-endophytes in Trichoderma

K Scott, Z Konkel, E Gluck-Thaler, GE Valero David… - PloS one, 2023 - journals.plos.org
Trichoderma is a cosmopolitan genus with diverse lifestyles and nutritional modes, including
mycotrophy, saprophytism, and endophytism. Previous research has reported greater …

Traits along the leaf economics spectrum are associated with communities of foliar endophytic symbionts

PH Tellez, AE Arnold, AB Leo, K Kitajima… - Frontiers in …, 2022 - frontiersin.org
Leaf traits of plants worldwide are classified according to the Leaf Economics Spectrum
(LES), which links leaf functional traits to evolutionary life history strategies. As a continuum …

CLOCI: unveiling cryptic fungal gene clusters with generalized detection

Z Konkel, L Kubatko, JC Slot - Nucleic Acids Research, 2024 - academic.oup.com
Gene clusters are genomic loci that contain multiple genes that are functionally and
genetically linked. Gene clusters collectively encode diverse functions, including small …

Genome sequencing and molecular networking analysis of the wild fungus Anthostomella pinea reveal its ability to produce a diverse range of secondary metabolites

R Iacovelli, T He, JL Allen, T Hackl… - Fungal Biology and …, 2024 - Springer
Background Filamentous fungi are prolific producers of bioactive molecules and enzymes
with important applications in industry. Yet, the vast majority of fungal species remain …

Applying molecular and genetic methods to trees and their fungal communities

M Müller, U Kües, KB Budde, O Gailing - Applied Microbiology and …, 2023 - Springer
Forests provide invaluable economic, ecological, and social services. At the same time, they
are exposed to several threats, such as fragmentation, changing climatic conditions, or …

Terabase-scale coassembly of a tropical soil microbiome

R Riley, RM Bowers, AP Camargo… - Microbiology …, 2023 - Am Soc Microbiol
Petabases of environmental metagenomic data are publicly available, presenting an
opportunity to characterize complex environments and discover novel lineages of life …