The clinical phenotypic variability seen in BAV patients suggests complex interactions
between genetic variants, epigenetic regulation modifications and the variable effect of valve …

Background A bicuspid aortic valve (BAV) is the most common congenital cardiac
malformation and is associated with ascending aortic dilation in 60%–80% of patients. In this …

Background: The limitation of aortic size-based criteria is gradually recognized in the
prediction of aortic events especially in bicuspid aortic valve (BAV) cohorts, while most aortic …

Background Patients with a bicuspid aortic valve (BAV) are at risk of developing valve
deterioration and aortic dilatation. We aimed to investigate whether blood biomarkers are …

The ascending aorta dilatation in the bicuspid aortic valve (BAV) patients is often attributed
to congenital abnormalities of the aortic wall, but it may be related to hemodynamic …

Serological biomarkers are a novel and promising diagnostic tool for screening thoracic
aortic aneurysmal disease and prediction future adverse aortic events. In combination with …

There is growing clinical need and interest to implement novel risk prediction tools in
bicuspid aortic valve-associated proximal aortic disease, so-called bicuspid aortic valve …

We read with interest the study by Liu and coworkers in which they have addressed the role
of hemodynamics in the development of aortopathy in bicuspid aortic valve (BAV) patients …

Bicuspid aortic valve (BAV) is the most common congenital heart defect with an estimated
prevalence of 1–2%. It is now common knowledge that BAV is associated with aortic …

The decision to undertake thoracic aortic repair in patients with progressive aortic dilation in
the setting of bicuspid aortic valvular disease remains a point of much discussion and …