Engineering a transaminase for the efficient synthesis of a key intermediate for rimegepant

Y Ma, X Jiao, Z Wang, H Mu, K Sun, X Li… - … Process Research & …, 2022 - ACS Publications
Transaminases have been increasingly utilized as efficient biocatalysts in the synthesis of
pharmaceutical intermediates, but a major drawback is their poor substrate acceptance …

A new approach to migraines-A review of rimegepant; its merits, synthesis, and pharmacological characteristics

G Tomšič - 2022 - chemrxiv.org
Migraines in the modern day represent a significant problem, however, the current treatment
options come with significant risks. This paper reviews rimegepant, its pharmacological …