Nanomechanical mapping of soft materials with the atomic force microscope: methods, theory and applications

R Garcia - Chemical Society Reviews, 2020 - pubs.rsc.org
Fast, high-resolution, non-destructive and quantitative characterization methods are needed
to develop materials with tailored properties at the nanoscale or to understand the …

Atomic force microscopy-based mechanobiology

M Krieg, G Fläschner, D Alsteens, BM Gaub… - Nature Reviews …, 2019 - nature.com
Mechanobiology emerges at the crossroads of medicine, biology, biophysics and
engineering and describes how the responses of proteins, cells, tissues and organs to …

Highly stretchable and self-healing cellulose nanofiber-mediated conductive hydrogel towards strain sensing application

Y Jiao, Y Lu, K Lu, Y Yue, X Xu, H Xiao, J Li… - Journal of Colloid and …, 2021 - Elsevier
Hypothesis Hydrogel-based sensors have attracted considerable attention due to potential
opportunities in human health monitoring when both mechanical flexibility and sensing …

Measuring viscoelasticity of soft biological samples using atomic force microscopy

YM Efremov, T Okajima, A Raman - Soft matter, 2020 - pubs.rsc.org
Mechanical properties play important roles at different scales in biology. At the level of a
single cell, the mechanical properties mediate mechanosensing and mechanotransduction …

Nanorheology of living cells measured by AFM-based force–distance curves

PD Garcia, CR Guerrero, R Garcia - Nanoscale, 2020 - pubs.rsc.org
Mechanobiology aims to establish functional relationships between the mechanical state of
a living a cell and its physiology. The acquisition of force–distance curves with an AFM is by …

Fast, quantitative and high resolution mapping of viscoelastic properties with bimodal AFM

S Benaglia, CA Amo, R Garcia - Nanoscale, 2019 - pubs.rsc.org
Quantitative mapping of viscoelastic properties of soft matter with a nanoscale spatial
resolution is an active and relevant research topic in atomic force microscopy (AFM) and …

Subsurface imaging of cell organelles by force microscopy

CR Guerrero, PD Garcia, R Garcia - ACS nano, 2019 - ACS Publications
The development of high-resolution, label-free, noninvasive, and subsurface microscopy
methods of living cells remains a formidable problem. Force-microscopy-based stiffness …

Double power-law viscoelastic relaxation of living cells encodes motility trends

JS De Sousa, RS Freire, FD Sousa, M Radmacher… - Scientific reports, 2020 - nature.com
Living cells are constantly exchanging momentum with their surroundings. So far, there is no
consensus regarding how cells respond to such external stimuli, although it reveals much …

Viscoelastic mapping of cells based on fast force volume and PeakForce Tapping

YM Efremov, AI Shpichka, SL Kotova, PS Timashev - Soft Matter, 2019 - pubs.rsc.org
Development of fast force volume (FFV), PeakForce Tapping (PFT), and related AFM
techniques allow fast acquisition and mapping of a sample's mechanical properties. The …

Determination of the viscoelastic properties of a single cell cultured on a rigid support by force microscopy

PD Garcia, R Garcia - Nanoscale, 2018 - pubs.rsc.org
Understanding the relationship between the mechanical properties of living cells and
physiology is a central issue in mechanobiology. Mechanical properties are used as …