Heavy metals and human health: mechanistic insight into toxicity and counter defense system of antioxidants

AT Jan, M Azam, K Siddiqui, A Ali, I Choi… - International journal of …, 2015 - mdpi.com
Heavy metals, which have widespread environmental distribution and originate from natural
and anthropogenic sources, are common environmental pollutants. In recent decades, their …

Chelation in metal intoxication

SJS Flora, V Pachauri - … journal of environmental research and public …, 2010 - mdpi.com
Chelation therapy is the preferred medical treatment for reducing the toxic effects of metals.
Chelating agents are capable of binding to toxic metal ions to form complex structures which …

Oxidative stress in lead and cadmium toxicity and its amelioration

RC Patra, AK Rautray, D Swarup - Veterinary medicine …, 2011 - Wiley Online Library
Oxidative stress has been implicated to play a role, at least in part, in pathogenesis of many
disease conditions and toxicities in animals. Overproduction of reactive oxygen species and …

Lead toxicity part II: the role of free radical damage and the use of antioxidants in the pathology and treatment of lead toxicity.

L Patrick - Alternative medicine review, 2006 - search.ebscohost.com
Lead is an environmentally persistent toxin that causes neurological, hematological,
gastrointestinal, reproductive, circulatory, and immunological pathologies. The propensity for …

Antioxidant nutrients and lead toxicity

PC Hsu, YL Guo - Toxicology, 2002 - Elsevier
Lead-induced oxidative stress contributes to the pathogenesis of lead poisoning for
disrupting the delicate prooxidant/antioxidant balance that exists within mammalian cells …

Can antioxidants be beneficial in the treatment of lead poisoning?

H Gurer, N Ercal - Free Radical Biology and Medicine, 2000 - Elsevier
Recent studies have shown that lead causes oxidative stress by inducing the generation of
reactive oxygen species, reducing the antioxidant defense system of cells via depleting …

Selenium and zinc protections against metal-(loids)-induced toxicity and disease manifestations: a review

MM Rahman, KFB Hossain, S Banik, MT Sikder… - Ecotoxicology and …, 2019 - Elsevier
Metals are ubiquitous in the environment due to huge industrial applications in the form of
different chemicals and from extensive mining activities. The frequent exposures to metals …

Strategies for safe and effective therapeutic measures for chronic arsenic and lead poisoning

K Kalia, SJS Flora - Journal of occupational health, 2005 - Wiley Online Library
Strategies for Safe and Effective Therapeutic Measures for Arsenic and Lead Poisoning:
Kiran Kalia, et al. Department of Biosciences, Sardar Patel University, India—Exposure to …

Environmental lead toxicity and nutritional factors

M Ahamed, MKJ Siddiqui - Clinical nutrition, 2007 - Elsevier
Environmental lead toxicity is an old but persistent public health problem throughout the
world and children are more susceptible to lead than adults because of their hand to mouth …

The role of AGEs and AGE inhibitors in diabetic cardiovascular disease

MC Thomas, JW Baynes, SR Thorpe… - Current drug …, 2005 - ingentaconnect.com
Prolonged hyperglycemia, dyslipidemia and oxidative stress in diabetes result in the
production and accumulation of AGEs. It is now clear that AGEs contribute to the …