Furan- and Furopyrimidine-Based Derivatives: Synthesis, VEGFR-2 Inhibition, and In Vitro Cytotoxicity
AH Abd El-Haleem, MAE Kassem… - ACS Medicinal …, 2024 - ACS Publications
New derivatives 4a–d, 6, 7a–d, 8a–c, 9, 11a, 11b, 12a–f, 13a–c, and 14 were synthesized
and evaluated for their VEGFR-2 inhibition. Compounds 4c, 7b, and 7c showed remarkable …
and evaluated for their VEGFR-2 inhibition. Compounds 4c, 7b, and 7c showed remarkable …
Novel Furan and Furo[2,3–d]pyrimidinone Analogues: Cytotoxicity, Antioxidant, and Bleomycin‐Dependent DNA Damage Assessment
T Musbah, NS Mohammed, A El‐Mekabaty - ChemistrySelect, 2023 - Wiley Online Library
Abstract Ethyl 2‐amino‐4, 5‐diphenylfuran‐3‐carboxylate (2), a reactive synthon, was
successfully used to synthesize a novel series of furan and furo [2, 3–d] pyrimidinone …
successfully used to synthesize a novel series of furan and furo [2, 3–d] pyrimidinone …
Novel phthalimide-pyrimidine hybrids as potent anti-tubercular agents
W Shehta, NA Alsaiari, B Farag, MM Abdel-Aziz… - 2024 - researchsquare.com
Condensation reaction of aromatic aldehydes with 2-(6-amino-2-chloropyrimidin-4-yl)
isoindoline-1, 3-dione and 2-(6-amino-2-hydrazineylpyrimidin-4-yl) isoindoline-1, 3-dione …
isoindoline-1, 3-dione and 2-(6-amino-2-hydrazineylpyrimidin-4-yl) isoindoline-1, 3-dione …
[PDF][PDF] SYNTHESIS AND EVALUATION OF THE ANTICANCER ACTIVITY OF 2-AMINOISOINDOLE-THIZOLIDINONE HYBRIDS
The aim of the work. Synthesis 2-aminoisoindole thizolidinone derivatives via [2+ 3]-
cyclocondensation reaction using different equivalents of electrophilic synthon [C2] 2+ and …
cyclocondensation reaction using different equivalents of electrophilic synthon [C2] 2+ and …
СИНТЕЗ ТА ОЦІНКА ПРОТИПУХЛОВОЇ АКТИВНОСТІ 2-АМІНОІЗОІНДОЛ ТІАЗОЛІДИНОНОВИХ ГІБРИДІВ
Анотація Мета роботи. Синтез похідних 2-аміноізоіндол тіазолідинону шляхом реакції
[2+ 3]-циклоконденсації шляхом використання різноманітних еквівалентів …
[2+ 3]-циклоконденсації шляхом використання різноманітних еквівалентів …