Diabetes mellitus predisposes affected individuals to a significant spectrum of
cardiovascular complications, one of the most debilitating in terms of prognosis is heart …

Cardiovascular diseases create an important burden on the public health systems,
especially in the elderly, mostly because this group of patients frequently suffer from multiple …

Reactive oxygen species (ROS) are highly reactive chemical species containing oxygen,
controlled by both enzymatic and nonenzymatic antioxidant defense systems. In the heart …

Type 1 diabetes mellitus (T1DM), also known as autoimmune diabetes, is a chronic disease
characterized by insulin deficiency due to pancreatic β-cell loss and leads to …

Left ventricular (LV) ejection fraction (LVEF) is a simple measure of global systolic function
that pervades the risk evaluation and management of many cardiovascular diseases …

Diabetes is a disorder of glucose metabolism, and over 90% are type 2 diabetes. Diabetic
cardiomyopathy (DCM) is one of the type 2 diabetes complications, usually accompanied by …

Targeting mitochondrial quality control with melatonin has been found promising for
attenuating diabetic cardiomyopathy (DCM), although the underlying mechanisms remain …

The prevalence of cardiovascular disease (CVD) is increasing over time. CVD is a
comorbidity in diabetes and contributes to premature death. Citrus flavonoids possess …

(CVD) in individuals with type 1 diabetes mellitus (T1DM), the pathophysiology underlying
the relationship between cardiovascular events, CVD risk factors, and T1DM is not well …

Diabetes is a metabolic disorder affecting large percentage of population worldwide. NF-κβ
plays key role in pathogenesis of vascular complications of diabetes. Persistent …