Increasing evidence indicates that ovarian hormones affect brain structure, chemistry and
function of women in their reproductive age, potentially shaping their behavior and mental …

The menstrual cycle has attracted research interest ever since the 1930s. For many
researchers the menstrual cycle is an excellent model of ovarian steroid influence on …

Ovarian hormones are pivotal for the physiological maintenance of the brain function as well
as its response to environmental stimuli. There is mounting evidence attesting the relevance …

Women worldwide are two to three times more likely to suffer from depression in their
lifetime than are men. Female risk for depressive symptoms is particularly high during the …

Fluctuations in progesterone (P4) and estradiol (E2) across the menstrual cycle can exert
direct effects on biological systems implicated in neuropsychiatric disorders and represent a …

Endocrine organizational and activational influences on cognitive and affective circuits are
likely critical to the development of premenstrual dysphoric disorder (PMDD), a sex-specific …

Ovarian hormones, particularly 17β-estradiol, are involved in numerous neurophysiological
and neurochemical processes, including those subserving cognitive function. Estradiol plays …

Premenstrual dysphoric disorder (PMDD) afflicts 3%‐5% of women of childbearing age, and
is characterised by recurrent negative mood symptoms (eg, irritability, depression, anxiety …

Premenstrual dysphoric disorder (PMDD) is a female-specific condition classified in the
Diagnostic and Statical Manual—5th edition under depressive disorders. Alterations in grey …

The World Health Organization (WHO) and American Psychiatric Association (APA) have
recognised premenstrual dysphoric disorder (PMDD) as an independent diagnostic entity …