Messenger RNA (mRNA) vaccines against COVID‐19 are the first authorized biological
preparations developed using this platform. During the pandemic, their administration has …

SARS-CoV-2-specific T cell response has been proven essential for viral clearance, COVID-
19 outcome and long-term memory. Impaired early T cell-driven immunity leads to a severe …

To elicit optimal immune responses, messenger RNA vaccines require intracellular delivery
of the mRNA and the careful use of adjuvants. Here we report a multiply adjuvanted mRNA …

Suboptimal immunity to SARS-CoV-2 mRNA vaccination has frequently been observed in
individuals with various immunodeficiencies. Given the increased antibody evasion …

T cell responses play an important role in protection against beta-coronavirus infections,
including SARS-CoV-2, where they associate with decreased COVID-19 disease severity …

Unlike mRNA vaccines based only on the spike protein, inactivated severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) vaccines should induce a diversified T cell …

Herd immunity achieved through mass vaccination is an effective approach to prevent
contagious diseases. Nonetheless, emerging SARS-CoV-2 variants with frequent mutations …

SARS-CoV-2 infection induces the generation of virus-specific CD4+ and CD8+ effector and
memory T cells. However, the contribution of T cells in controlling SARS-CoV-2 during …

T cells are critical in mediating the early control of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) breakthrough infection. However, it remains unknown whether …

A mucosal route of vaccination could prevent severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) replication at the site of infection and limit transmission. We …