Revolutionizing disease modeling: the emergence of organoids in cellular systems
R Silva-Pedrosa, AJ Salgado, PE Ferreira - Cells, 2023 - mdpi.com
Cellular models have created opportunities to explore the characteristics of human diseases
through well-established protocols, while avoiding the ethical restrictions associated with …
through well-established protocols, while avoiding the ethical restrictions associated with …
Navigating environmental transitions: the role of phenotypic variation in bacterial responses
The ability of bacteria to respond to changes in their environment is critical to their survival,
allowing them to withstand stress, form complex communities, and induce virulence …
allowing them to withstand stress, form complex communities, and induce virulence …
Building a tissue: mesenchymal and epithelial cell spheroids mechanical properties at micro-and nanoscale
NV Kosheleva, YM Efremov, PI Koteneva, IV Ilina… - Acta Biomaterialia, 2023 - Elsevier
Cell transitions between the epithelial and mesenchymal phenotypes provide the regulated
morphogenesis and regeneration throughout the ontogenesis. The tissue mechanics and …
morphogenesis and regeneration throughout the ontogenesis. The tissue mechanics and …
[HTML][HTML] Role of MAIT cells in gastrointestinal tract bacterial infections in humans: More than a gut feeling
Y Zheng, F Han, A Ho, Y Xue, Z Wu, X Chen… - Mucosal …, 2023 - Elsevier
Mucosa-associated invariant T (MAIT) cells are the largest population of unconventional T
cells in humans. These antimicrobial T cells are poised with rapid effector responses …
cells in humans. These antimicrobial T cells are poised with rapid effector responses …
3D multicellular systems in disease modelling: From organoids to organ-on-chip
C Goldrick, I Guri, G Herrera-Oropeza… - Frontiers in Cell and …, 2023 - frontiersin.org
Cell-cell interactions underlay organ formation and function during homeostasis. Changes in
communication between cells and their surrounding microenvironment are a feature of …
communication between cells and their surrounding microenvironment are a feature of …
Mimicking the liver function in micro-patterned units: Challenges and perspectives in 3D bioprinting
Abstract Bioprinting of 3-dimensional (3D) micro-patterned structures could be a promising
approach to mimic complex organs in vivo. This technique holds promise for generating …
approach to mimic complex organs in vivo. This technique holds promise for generating …
New drug discovery
B Yingngam - Multidisciplinary Applications of Natural Science for …, 2023 - igi-global.com
The field of drug discovery is continually advancing with the emergence of new technologies
and scientific developments. Moreover, there is a recent growing interest in exploiting …
and scientific developments. Moreover, there is a recent growing interest in exploiting …
Advances in organoid technology for veterinary disease modeling
B Chen, RF Slocombe, SR Georgy - Frontiers in Veterinary Science, 2023 - frontiersin.org
Organoids are in vitro organ-like structures that faithfully recapitulate many characteristics of
a specific organ. During the past decades, major progress has been accomplished in …
a specific organ. During the past decades, major progress has been accomplished in …
In vitro modelling of bacterial pneumonia: a comparative analysis of widely applied complex cell culture models
L Mahieu, L Van Moll, L De Vooght… - FEMS Microbiology …, 2024 - academic.oup.com
Bacterial pneumonia greatly contributes to the disease burden and mortality of lower
respiratory tract infections among all age groups and risk profiles. Therefore, laboratory …
respiratory tract infections among all age groups and risk profiles. Therefore, laboratory …
Application of stem cell-derived extracellular vesicles as an innovative theranostics in microbial diseases
H Keshavarz Alikhani, B Shokoohian… - Frontiers in …, 2021 - frontiersin.org
Extracellular vesicles (EVs), as nano-/micro-scale vehicles, are membranous particles
containing various cargoes including peptides, proteins, different types of RNAs and other …
containing various cargoes including peptides, proteins, different types of RNAs and other …