Light-triggered photodynamic nanomedicines for overcoming localized therapeutic efficacy in cancer treatment

J Choi, IC Sun, HS Hwang, HY Yoon, K Kim - Advanced Drug Delivery …, 2022 - Elsevier
Photodynamic nanomedicines have significantly enhanced the therapeutic efficacy of
photosensitizers (PSs) by overcoming critical limitations of PSs such as poor water solubility …

[HTML][HTML] Stimuli-responsive peptide assemblies: Design, self-assembly, modulation, and biomedical applications

R Mu, D Zhu, S Abdulmalik, S Wijekoon, G Wei… - Bioactive materials, 2024 - Elsevier
Peptide molecules have design flexibility, self-assembly ability, high biocompatibility, good
biodegradability, and easy functionalization, which promote their applications as versatile …

A spatiotemporal release platform based on pH/ROS stimuli-responsive hydrogel in wound repairing

Y Wu, Y Wang, L Long, C Hu, Q Kong… - Journal of Controlled …, 2022 - Elsevier
Fabricating injectable hydrogel with multifunctions that matchs the highly ordered healing
process of skin regeneration has greatly desired in treatment of chronic diabetic wounds …

Regeneration of infarcted hearts by myocardial infarction-responsive injectable hydrogels with combined anti-apoptosis, anti-inflammatory and pro-angiogenesis …

C Hu, W Liu, L Long, Z Wang, W Zhang, S He, L Lu… - Biomaterials, 2022 - Elsevier
Current treatments including drug therapy, medical device implantation, and organ
transplantation have considerable shortcomings for myocardial infarction (MI), such as high …

Co‐delivery CPT and PTX prodrug with a photo/thermo‐responsive nanoplatform for triple‐negative breast cancer therapy

W Zhou, X Ma, J Wang, X Xu, O Koivisto… - Smart …, 2022 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is still the most aggressive cancer in women.
Combination chemotherapy holds great potential for cancer therapy; however, the off‐target …

Dissolving microneedle-encapsulated drug-loaded nanoparticles and recombinant humanized collagen type III for the treatment of chronic wound via anti …

L Long, W Liu, L Li, C Hu, S He, L Lu, J Wang, L Yang… - Nanoscale, 2022 - pubs.rsc.org
Nowadays, diabetic chronic wounds impose a heavy burden on patients and the medical
system. Persistent inflammation and poor tissue remodeling severely limit the healing of …

Versatile peptide-based nanosystems for photodynamic therapy

Q Li, R Ming, L Huang, R Zhang - Pharmaceutics, 2024 - mdpi.com
Photodynamic therapy (PDT) has become an important therapeutic strategy because it is
highly controllable, effective, and does not cause drug resistance. Moreover, precise …

Microenvironment-responsive multifunctional hydrogels with spatiotemporal sequential release of tailored recombinant human collagen type III for the rapid repair of …

C Hu, W Liu, L Long, Z Wang, Y Yuan… - Journal of Materials …, 2021 - pubs.rsc.org
Recently, the incidence of chronic diabetic wounds increases continuously, and the existing
clinical treatment is less effective. Thus, it is an urgent need to solve these problems for …

Redox-responsive hyaluronic acid-based nanoparticles for targeted photodynamic therapy/chemotherapy against breast cancer

R Wang, H Yang, AR Khan, X Yang, J Xu, J Ji… - Journal of Colloid and …, 2021 - Elsevier
Specific cellular uptake and sufficient drug release in tumor tissues are important for
effective cancer therapy. Hyaluronic acid (HA), a skeleton material, could specifically bind to …

Light-enabled reversible shape transformation of block copolymer particles

D Hu, X Chang, Y Xu, Q Yu, Y Zhu - ACS Macro Letters, 2021 - ACS Publications
Confined self-assembly of block copolymers (BCPs) is effective to manipulate various
shapes of particles. In emulsion confined self-assembly, reversibly light-trigged switchable …