O-GlcNAc Signaling in the Cardiovascular System
GA Ngoh, HT Facundo, A Zafir, SP Jones - Circulation research, 2010 - Am Heart Assoc
Cardiovascular function is regulated at multiple levels. Some of the most important aspects
of such regulation involve alterations in an ever-growing list of posttranslational …
of such regulation involve alterations in an ever-growing list of posttranslational …
The chemical neurobiology of carbohydrates
HE Murrey, LC Hsieh-Wilson - Chemical reviews, 2008 - ACS Publications
The cell surface displays a complex array of oligosaccharides, glycoproteins, and
glycolipids. This diverse mixture of glycans contains a wealth of information, modulating a …
glycolipids. This diverse mixture of glycans contains a wealth of information, modulating a …
A small molecule that inhibits OGT activity in cells
RF Ortiz-Meoz, J Jiang, MB Lazarus… - ACS chemical …, 2015 - ACS Publications
O-GlcNAc transferase (OGT) is an essential mammalian enzyme that regulates numerous
cellular processes through the attachment of O-linked N-acetylglucosamine (O-GlcNAc) …
cellular processes through the attachment of O-linked N-acetylglucosamine (O-GlcNAc) …
Evidence of the involvement of O-GlcNAc-modified human RNA polymerase II CTD in transcription in vitro and in vivo
The RNA polymerase II C-terminal domain (CTD), which serves as a scaffold to recruit
machinery involved in transcription, is modified post-translationally. Although the O-GlcNAc …
machinery involved in transcription, is modified post-translationally. Although the O-GlcNAc …
O-GlcNAcylation, a sweet link to the pathology of diseases
H Nie, W Yi - Journal of Zhejiang University-SCIENCE B, 2019 - Springer
Abstract O-linked N-acetylglucosamine (O-GlcNAc) is a dynamic post-translational
modification occurring on myriad proteins in the cell nucleus, cytoplasm, and mitochondria …
modification occurring on myriad proteins in the cell nucleus, cytoplasm, and mitochondria …
[HTML][HTML] Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis
JA Groves, A Lee, G Yildirir, NE Zachara - Cell Stress and Chaperones, 2013 - Elsevier
O-linked N-acetyl-β-d-glucosamine (O-GlcNAc) is a ubiquitous and dynamic post-
translational modification known to modify over 3,000 nuclear, cytoplasmic, and …
translational modification known to modify over 3,000 nuclear, cytoplasmic, and …
O-GlcNAcylation of AMPA receptor GluA2 is associated with a novel form of long-term depression at hippocampal synapses
EW Taylor, K Wang, AR Nelson… - Journal of …, 2014 - Soc Neuroscience
Serine phosphorylation of AMPA receptor (AMPAR) subunits GluA1 and GluA2 modulates
AMPAR trafficking during long-term changes in strength of hippocampal excitatory …
AMPAR trafficking during long-term changes in strength of hippocampal excitatory …
Chemical approaches to understanding O-GlcNAc glycosylation in the brain
JE Rexach, PM Clark, LC Hsieh-Wilson - Nature chemical biology, 2008 - nature.com
O-GlcNAc glycosylation is a unique, dynamic form of glycosylation found on intracellular
proteins of all multicellular organisms. Studies suggest that O-GlcNAc represents a key …
proteins of all multicellular organisms. Studies suggest that O-GlcNAc represents a key …
Developmental regulation of protein O-GlcNAcylation, O-GlcNAc transferase, and O-GlcNAcase in mammalian brain
Y Liu, X Li, Y Yu, J Shi, Z Liang, X Run, Y Li, C Dai… - 2012 - journals.plos.org
O-GlcNAcylation is a common posttranslational modification of nucleocytoplasmic proteins
by β-N-acetylglucosamine (GlcNAc). The dynamic addition and removal of O-GlcNAc groups …
by β-N-acetylglucosamine (GlcNAc). The dynamic addition and removal of O-GlcNAc groups …
O-GlcNAcylation as a therapeutic target for Alzheimer's disease
Alzheimer's disease (AD) is the most common cause of dementia and the number of elderly
patients suffering from AD has been steadily increasing. Despite worldwide efforts to cope …
patients suffering from AD has been steadily increasing. Despite worldwide efforts to cope …