Traditionally, xenobiotic receptors are known for their role in chemical sensing and
detoxification, as receptor activation regulates the expression of various key enzymes and …

Plastics are complex chemical mixtures of polymers and various intentionally and
nonintentionally added substances. Despite the well-established links between certain …

Plastics constitute a vast array of substances, with over 16 000 known plastic chemicals,
including intentionally and non-intentionally added substances. Thousands of chemicals …

Background Phthalates are commonly used in variety of plastic products. Previously it has
been revealed that di (2-ethylhexyl) phthalate (DEHP), as the most common member of the …

Phthalic acid esters (PAEs), commonly used as plasticizers, are pervasive in the
environment, leading to widespread human exposure. The association between phthalate …

Abdominal aortic aneurysm (AAA) is a life-threatening condition, but effective medications to
prevent its progression and rupture are currently lacking. The nuclear receptor pregnane-X …

The effect of endothelial cells' exposure to dibutyl phthalate (DBP) on monocyte adhesion is
largely unknown. We evaluated monocyte adhesion to DBP-exposed endothelial cells by …

Emerging studies suggest that various parental exposures affect offspring cardiovascular
health, yet the specific mechanisms, particularly the influence of paternal cardiovascular …

One of the targets of the circular economy is to keep different materials and substances in
circulation for as long as possible. The need for fossil-based virgin materials is efficiently …

孕烷X 受体(pregnane X receptor, PXR) 是一种调控生物体异源性/内源性物质代谢的核受体.
环境污染物可介由PXR 改变人体代谢稳态进而增加多种代谢性疾病风险 …