[HTML][HTML] miRNA-based biomarkers, therapies, and resistance in Cancer
B He, Z Zhao, Q Cai, Y Zhang, P Zhang… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Abstract MicroRNAs (miRNAs), small non-coding RNAs (ncRNAs) of about 22 nucleotides in
size, play important roles in gene regulation, and their dysregulation is implicated in human …
size, play important roles in gene regulation, and their dysregulation is implicated in human …
Overview of microRNA biogenesis, mechanisms of actions, and circulation
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
METTL14 promotes doxorubicin-induced cardiomyocyte ferroptosis by regulating the KCNQ1OT1-miR-7-5p-TFRC axis
S Zhuang, Y Ma, Y Zeng, C Lu, F Yang, N Jiang… - Cell Biology and …, 2021 - Springer
Doxorubicin (DOX) has toxic effects on the heart, causing cardiomyopathy and heart injury,
but the underlying mechanisms of these effects require further investigation. This study …
but the underlying mechanisms of these effects require further investigation. This study …
miR‐30 family: a promising regulator in development and disease
L Mao, S Liu, L Hu, L Jia, H Wang… - BioMed research …, 2018 - Wiley Online Library
MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate posttranscriptional
expression of target genes. Accumulating evidences have demonstrated that the miR‐30 …
expression of target genes. Accumulating evidences have demonstrated that the miR‐30 …
Regulation and different functions of the animal microRNA‐induced silencing complex
PM Frédérick, MJ Simard - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Among the different types of small RNAs, microRNAs (miRNAs) are key players in
controlling gene expression at the mRNA level. To be active, they must associate with an …
controlling gene expression at the mRNA level. To be active, they must associate with an …
[HTML][HTML] NEAT1 and paraspeckles in neurodegenerative diseases: A missing lnc found?
H An, NG Williams, TA Shelkovnikova - Non-coding RNA research, 2018 - Elsevier
Neurodegenerative diseases are among the most common causes of disability worldwide.
Although neurodegenerative diseases are heterogeneous in both their clinical features and …
Although neurodegenerative diseases are heterogeneous in both their clinical features and …
Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis
TA Shelkovnikova, MS Kukharsky, H An… - Molecular …, 2018 - Springer
Background Paraspeckles are subnuclear bodies assembled on a long non-coding RNA
(lncRNA) NEAT1. Their enhanced formation in spinal neurons of sporadic amyotrophic …
(lncRNA) NEAT1. Their enhanced formation in spinal neurons of sporadic amyotrophic …
Loss of Sfpq causes long-gene transcriptopathy in the brain
A Takeuchi, K Iida, T Tsubota, M Hosokawa, M Denawa… - Cell Reports, 2018 - cell.com
Genes specifically expressed in neurons contain members with extended long introns.
Longer genes present a problem with respect to fulfilment of gene length transcription, and …
Longer genes present a problem with respect to fulfilment of gene length transcription, and …
MicroRNA mediated regulation of the major redox homeostasis switch, Nrf2, and its impact on oxidative stress-induced ischemic/reperfusion injury
G Padmavathi, KM Ramkumar - Archives of Biochemistry and Biophysics, 2021 - Elsevier
Ischemia/reperfusion injury (IRI) initiates from oxidative stress caused by lack of blood
supply and subsequent reperfusion. It is often associated with sterile inflammation, cell …
supply and subsequent reperfusion. It is often associated with sterile inflammation, cell …
Long noncoding RNA LHFPL3-AS2 suppresses metastasis of non-small cell lung cancer by interacting with SFPQ to regulate TXNIP expression
Z Cheng, C Lu, H Wang, N Wang, S Cui, C Yu, C Wang… - Cancer letters, 2022 - Elsevier
Lung cancer is the most common cancer and the leading cause of cancer deaths worldwide.
In addition to coding genes, the contribution of long noncoding RNA (lncRNA) to non-small …
In addition to coding genes, the contribution of long noncoding RNA (lncRNA) to non-small …