Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is capable of inducing the
activation of NACHT, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) …

Objective: We assessed the efficacy of colchicine in COVID-19 patients through a systematic
review. Methods: Six databases were searched until March 2022 for studies assessing …

We report herein an alternative method for the synthesis of seleno-dibenzocycloheptenones
and seleno-spiro [5.5] trienones through the radical cyclization of biaryl ynones in the …

Background Colchicine is an available, safe, and effective anti-inflammatory drug and has
been suggested as a COVID-19 treatment, but its usefulness in hospitalized severe COVID …

Abstract Angiotensin-converting enzyme 2 (ACE2) is a major cell entry receptor for severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The induction of ACE2 expression …

Aim This meta-analysis aimed to assess the usefulness of colchicine in patients with COVID-
19. Methods PubMed, Web of Science, Ovid MEDLINE, the Cochrane Library, Embase, and …

The impact of COVID-19 prompted a race to find a treatment that would reduce its mortality.
Most studies have not shown favorable results for many of these drugs, but they are still …

Colchicine is increasingly used as the number of potential indications expands. However, it
also has a narrow therapeutic index that is associated with bothersome to severe side …

Colchicine is one of the most widely studied and best‐known anti‐inflammatory treatments.
This study aimed to assess the effect of colchicine on risk of hospitalization due to COVID …

The innate immune system is critically involved in the pathogenesis of familial
Mediterranean fever (FMF), characterized by dysregulated inflammasome activity and …