Crosstalk between the gut microbiota and the host has attracted considerable attention
owing to its involvement in diverse diseases. Chronic kidney disease (CKD) is commonly …

Highlights•Stress/depression and diet independently and jointly shape the gut
microbiota.•The gut bacteria can modulate food cravings, stress reactivity, and mood.•These …

Protein arginine methyltransferase (PRMT) 5 is over-expressed in a variety of cancers and
the master transcription regulator E2F1 is an important methylation target. We have explored …

Association between gut dysbiosis and neurogenic diseases, such as hypertension, has
been described. The aim of this study was to investigate whether changes in the gut …

Aim Butyrate is a major gut microbiota‐derived metabolite. Reduced butyrate‐producing
bacteria has been reported in the spontaneously hypertensive rat (SHR), a model of …

Background We have demonstrated that the antihypertensive effect of the angiotensin‐
converting enzyme inhibitor, captopril (CAP), is associated with beneficial effects on gut …

Inflammatory bowel diseases (IBD) have a complex, multifactorial pathophysiology with an
unmet need for effective treatment. This calls for novel strategies to improve disease …

Aims The effect of the gut microbiota (GM) and its metabolite on bone health is termed the
gut-bone axis. Multiple studies have elucidated the mechanisms but findings vary greatly. A …

Hypertension (HTN) is an escalating health issue worldwide. It is estimated that 1.56 billion
people will suffer from high blood pressure (BP) by 2025. Recent studies reported an …

Inflammation and gut dysbiosis are hallmarks of hypertension (HTN). Hydrogen sulfide (H 2
S) is an important freely diffusing molecule that modulates the function of neural …