The roles of androgens in humans: biology, metabolic regulation and health

M Alemany - International journal of molecular sciences, 2022 - mdpi.com
Androgens are an important and diverse group of steroid hormone molecular species. They
play varied functional roles, such as the control of metabolic energy fate and partition, the …

[HTML][HTML] Testosterone: a metabolic hormone in health and disease

DM Kelly, TH Jones - Journal of Endocrinology, 2013 - joe.bioscientifica.com
Testosterone is a hormone that plays a key role in carbohydrate, fat and protein metabolism.
It has been known for some time that testosterone has a major influence on body fat …

The anti-inflammatory effects of testosterone

VE Bianchi - Journal of the endocrine society, 2019 - academic.oup.com
Low plasma testosterone (T) levels correlated with metabolic syndrome, cardiovascular
diseases, and increased mortality risk. T exerts a significant effect on the regulation of …

Cardiovascular risk associated with testosterone-boosting medications: a systematic review and meta-analysis

G Corona, E Maseroli, G Rastrelli… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Recent reports have significantly halted the enthusiasm regarding androgen-
boosting; suggesting that testosterone supplementation (TS) increases cardiovascular (CV) …

Lowered testosterone in male obesity: mechanisms, morbidity and management

MNT Fui, P Dupuis, M Grossmann - Asian journal of andrology, 2014 - journals.lww.com
With increasing modernization and urbanization of Asia, much of the future focus of the
obesity epidemic will be in the Asian region. Low testosterone levels are frequently …

Therapy of endocrine disease: testosterone supplementation and body composition: results from a meta-analysis study

G Corona, VA Giagulli, E Maseroli… - European Journal of …, 2016 - academic.oup.com
Objective The role of testosterone (T) in regulating body composition is conflicting. Thus, our
goal is to meta-analyse the effects of T supplementation (TS) on body composition and …

[HTML][HTML] Testosterone metabolites differentially regulate obesogenesis and fat distribution

ZL Sebo, MS Rodeheffer - Molecular metabolism, 2021 - Elsevier
Objective Low testosterone in men (hypogonadism) is associated with obesity and type II
diabetes. Testosterone replacement therapy has been shown to reverse these effects …

[HTML][HTML] Testosterone and weight loss: the evidence

AM Traish - Current Opinion in Endocrinology, Diabetes and …, 2014 - journals.lww.com
The implication of testosterone therapy in management of obesity in men with testosterone
deficiency is of paramount clinical significance, as it produces sustained weight loss without …

Cardiovascular risks of exogenous testosterone use among men: a systematic review and meta-analysis

GC Alexander, G Iyer, E Lucas, D Lin… - The American journal of …, 2017 - Elsevier
Purpose We sought to evaluate whether exogenous testosterone therapy is associated with
increased risk of serious cardiovascular events as compared with other treatments or …

Body compositional and cardiometabolic effects of testosterone therapy in obese men with severe obstructive sleep apnoea: a randomised placebo-controlled trial

CM Hoyos, BJ Yee, CL Phillips… - European journal of …, 2012 - academic.oup.com
Background The combination of male gender, obstructive sleep apnoea (OSA) and obesity
magnifies cardiometabolic risk. There has been no systematic study evaluating whether …