Colorectal cancer (CRC) is a heterogeneous disease that commonly affects individuals
aged more than 50 years old globally. Regular colorectal screening, which is recommended …

Worldwide deaths from diabetes mellitus (DM) and colorectal cancer increased by 90% and
57%, respectively, over the past 20 years. The risk of colorectal cancer was estimated to be …

Background & Aims The incidence of colorectal cancer (CRC) is increasing in the United
States among adults younger than the age of 50 years. Studies of young-onset CRC have …

Early onset colorectal cancers, defined as arising before 50 years of age, are a growing
health hazard in western and eastern countries alike. The incidence of colon and rectal …

Based on experimental and animal models, epidemiological data from non-acromegaly
populations, and longitudinal and cross-sectional cohorts of patients with acromegaly, a …

Simple Summary Colorectal cancer progression involves multi-gene aberration of several
biomarkers via the downstream regulation of the MARK/ERK cascade. GNAS gene mutation …

Colon cancer remains a leading cause of cancer-related deaths, and there has been a rise
in the incidence of early-onset colon cancer or colon cancer diagnosed before the age of 50 …

Colorectal cancer (CRC) is mostly due to a series of genetic alterations that are being
greatly under the influence of the environmental factors. These changes, mutational or …

Common genetic risk variants for colorectal cancer (CRC) have been identified at
approximately 40 loci by genome-wide association studies (GWAS). We investigated the …

AIM: Our aim was to determine whether MGMT promoter methylation might be detectable in
circulating free DNA in the serum of CRC patients and normal individuals using a …