[HTML][HTML] The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …
devastating consequences. While the medical community has gained insight into the …
[HTML][HTML] Immune determinants of COVID-19 disease presentation and severity
P Brodin - Nature medicine, 2021 - nature.com
Abstract COVID-19, caused by SARS-CoV-2 infection, is mild to moderate in the majority of
previously healthy individuals, but can cause life-threatening disease or persistent …
previously healthy individuals, but can cause life-threatening disease or persistent …
COVID-19 in immunocompromised hosts: what we know so far
M Fung, JM Babik - Clinical Infectious Diseases, 2021 - academic.oup.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused significant morbidity and …
respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused significant morbidity and …
Humoral and T-cell responses to SARS-CoV-2 vaccination in patients receiving immunosuppression
M Prendecki, C Clarke, H Edwards… - Annals of the …, 2021 - ard.bmj.com
Objective There is an urgent need to assess the impact of immunosuppressive therapies on
the immunogenicity and efficacy of SARS-CoV-2 vaccination. Methods Serological and T …
the immunogenicity and efficacy of SARS-CoV-2 vaccination. Methods Serological and T …
[HTML][HTML] SARS-CoV-2 mRNA vaccines: immunological mechanism and beyond
To successfully protect against pathogen infection, a vaccine must elicit efficient adaptive
immunity, including B and T cell responses. While B cell responses are key, as they can …
immunity, including B and T cell responses. While B cell responses are key, as they can …
COVID-19 in patients with primary and secondary immunodeficiency: the United Kingdom experience
Background As of November 2020, severe acute respiratory syndrome coronavirus 2 has
resulted in 55 million infections worldwide and more than 1.3 million deaths from …
resulted in 55 million infections worldwide and more than 1.3 million deaths from …
Immunogenicity of Pfizer-BioNTech COVID-19 vaccine in patients with inborn errors of immunity
D Hagin, T Freund, M Navon, T Halperin, D Adir… - Journal of Allergy and …, 2021 - Elsevier
Background In mid-December 2020, Israel started a nationwide mass vaccination campaign
against coronavirus disease 2019 (COVID-19). In the first few weeks, medical personnel …
against coronavirus disease 2019 (COVID-19). In the first few weeks, medical personnel …
[HTML][HTML] Coronavirus disease 2019 in patients with inborn errors of immunity: an international study
Background There is uncertainty about the impact of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection in individuals with rare inborn errors of immunity (IEI) …
coronavirus 2 (SARS-CoV-2) infection in individuals with rare inborn errors of immunity (IEI) …
[HTML][HTML] The immune response to SARS-CoV-2 and COVID-19 immunopathology–current perspectives
JL Boechat, I Chora, A Morais, L Delgado - Pulmonology, 2021 - Elsevier
SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …
Immunity to SARS‐CoV‐2 induced by infection or vaccination
Adaptive immune responses play critical roles in viral clearance and protection against re‐
infection, and SARS‐CoV‐2 is no exception. What is exceptional is the rapid …
infection, and SARS‐CoV‐2 is no exception. What is exceptional is the rapid …