[HTML][HTML] The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …

[HTML][HTML] Immune determinants of COVID-19 disease presentation and severity

P Brodin - Nature medicine, 2021 - nature.com
Abstract COVID-19, caused by SARS-CoV-2 infection, is mild to moderate in the majority of
previously healthy individuals, but can cause life-threatening disease or persistent …

COVID-19 in immunocompromised hosts: what we know so far

M Fung, JM Babik - Clinical Infectious Diseases, 2021 - academic.oup.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused significant morbidity and …

Humoral and T-cell responses to SARS-CoV-2 vaccination in patients receiving immunosuppression

M Prendecki, C Clarke, H Edwards… - Annals of the …, 2021 - ard.bmj.com
Objective There is an urgent need to assess the impact of immunosuppressive therapies on
the immunogenicity and efficacy of SARS-CoV-2 vaccination. Methods Serological and T …

[HTML][HTML] SARS-CoV-2 mRNA vaccines: immunological mechanism and beyond

E Bettini, M Locci - Vaccines, 2021 - mdpi.com
To successfully protect against pathogen infection, a vaccine must elicit efficient adaptive
immunity, including B and T cell responses. While B cell responses are key, as they can …

COVID-19 in patients with primary and secondary immunodeficiency: the United Kingdom experience

AM Shields, SO Burns, S Savic, AG Richter… - Journal of Allergy and …, 2021 - Elsevier
Background As of November 2020, severe acute respiratory syndrome coronavirus 2 has
resulted in 55 million infections worldwide and more than 1.3 million deaths from …

Immunogenicity of Pfizer-BioNTech COVID-19 vaccine in patients with inborn errors of immunity

D Hagin, T Freund, M Navon, T Halperin, D Adir… - Journal of Allergy and …, 2021 - Elsevier
Background In mid-December 2020, Israel started a nationwide mass vaccination campaign
against coronavirus disease 2019 (COVID-19). In the first few weeks, medical personnel …

[HTML][HTML] Coronavirus disease 2019 in patients with inborn errors of immunity: an international study

I Meyts, G Bucciol, I Quinti, B Neven, A Fischer… - Journal of Allergy and …, 2021 - Elsevier
Background There is uncertainty about the impact of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection in individuals with rare inborn errors of immunity (IEI) …

[HTML][HTML] The immune response to SARS-CoV-2 and COVID-19 immunopathology–current perspectives

JL Boechat, I Chora, A Morais, L Delgado - Pulmonology, 2021 - Elsevier
SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …

Immunity to SARS‐CoV‐2 induced by infection or vaccination

X Castro Dopico, S Ols, K Loré… - Journal of internal …, 2022 - Wiley Online Library
Adaptive immune responses play critical roles in viral clearance and protection against re‐
infection, and SARS‐CoV‐2 is no exception. What is exceptional is the rapid …