Aminoacyl-tRNA synthesis
▪ Abstract Aminoacyl-tRNAs are substrates for translation and are pivotal in determining how
the genetic code is interpreted as amino acids. The function of aminoacyl-tRNA synthesis is …
the genetic code is interpreted as amino acids. The function of aminoacyl-tRNA synthesis is …
Aminoacyl-tRNA synthetases: Structure, function, and drug discovery
Aminoacyl-tRNA synthetases (AARSs) are the enzymes that catalyze the aminoacylation
reaction by covalently linking an amino acid to its cognate tRNA in the first step of protein …
reaction by covalently linking an amino acid to its cognate tRNA in the first step of protein …
Protein analysis by dynamic light scattering: Methods and techniques for students
Dynamic light scattering (DLS) analyses are routinely used in biology laboratories to detect
aggregates in macromolecular solutions, to determine the size of proteins, nucleic acids …
aggregates in macromolecular solutions, to determine the size of proteins, nucleic acids …
Bacterial transfer rnas
J Shepherd, M Ibba - FEMS microbiology reviews, 2015 - academic.oup.com
Transfer RNA is an essential adapter molecule that is found across all three domains of life.
The primary role of transfer RNA resides in its critical involvement in the accurate translation …
The primary role of transfer RNA resides in its critical involvement in the accurate translation …
From one amino acid to another: tRNA-dependent amino acid biosynthesis
K Sheppard, J Yuan, MJ Hohn, B Jester… - Nucleic acids …, 2008 - academic.oup.com
Abstract Aminoacyl-tRNAs (aa-tRNAs) are the essential substrates for translation. Most aa-
tRNAs are formed by direct aminoacylation of tRNA catalyzed by aminoacyl-tRNA …
tRNAs are formed by direct aminoacylation of tRNA catalyzed by aminoacyl-tRNA …
Structural diversity and protein engineering of the aminoacyl-tRNA synthetases
JJ Perona, A Hadd - Biochemistry, 2012 - ACS Publications
Aminoacyl-tRNA synthetases (aaRS) are the enzymes that ensure faithful transmission of
genetic information in all living cells, and are central to the developing technologies for …
genetic information in all living cells, and are central to the developing technologies for …
Thermus thermophilus: A link in evolution of the tRNA-dependent amino acid amidation pathways
HD Becker, D Kern - … of the National Academy of Sciences, 1998 - National Acad Sciences
Thermus thermophilus possesses an aspartyl-tRNA synthetase (AspRS2) able to aspartylate
efficiently tRNAAsp and tRNAAsn. Aspartate mischarged on tRNAAsn then is converted into …
efficiently tRNAAsp and tRNAAsn. Aspartate mischarged on tRNAAsn then is converted into …
Evolution and variation in amide aminoacyl‐tRNA synthesis
The amide proteogenic amino acids, asparagine and glutamine, are two of the twenty amino
acids used in translation by all known life. The aminoacyl‐tRNA synthetases for asparagine …
acids used in translation by all known life. The aminoacyl‐tRNA synthetases for asparagine …
Glutamyl-tRNAGln amidotransferase in Deinococcus radiodurans may be confined to asparagine biosynthesis
AW Curnow, DL Tumbula… - Proceedings of the …, 1998 - National Acad Sciences
Asparaginyl-tRNA (Asn-tRNA) and glutaminyl-tRNA (Gln-tRNA) are essential components of
protein synthesis. They can be formed by direct acylation by asparaginyl-tRNA synthetase …
protein synthesis. They can be formed by direct acylation by asparaginyl-tRNA synthetase …
[HTML][HTML] Aminoacyl‐tRNA synthetases: a family of expanding functionsMittelwihr, France, October 10–15, 1999
SA Martinis, P Plateau, J Cavarelli, C Florentz - The EMBO journal, 1999 - embopress.org
The aminoacyl‐tRNA synthetases (aaRSs) are a family of enzymes well known for their role
in protein synthesis. More recent investigations have discovered that this classic family of …
in protein synthesis. More recent investigations have discovered that this classic family of …