[HTML][HTML] Oxidative stress and diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications

Q Kang, C Yang - Redox biology, 2020 - Elsevier
Oxidative stress, a cytopathic outcome of excessive generation of ROS and the repression of
antioxidant defense system for ROS elimination, is involved in the pathogenesis of multiple …

Mechanistic pathogenesis of endothelial dysfunction in diabetic nephropathy and retinopathy

J Yang, Z Liu - Frontiers in endocrinology, 2022 - frontiersin.org
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of
diabetes. Microvascular endothelial cells are thought to be the major targets of …

Role of oxidative stress in retinal disease and the early intervention strategies: a review

J Wang, M Li, Z Geng, S Khattak, X Ji… - … Medicine and Cellular …, 2022 - Wiley Online Library
The retina, owing to its cellular anatomy and physical location, is susceptible to generating
reactive oxygen species (ROS), which are associated with several major retinal diseases …

Berberine: a review of its pharmacokinetics properties and therapeutic potentials in diverse vascular diseases

X Ai, P Yu, L Peng, L Luo, J Liu, S Li, X Lai… - Frontiers in …, 2021 - frontiersin.org
Traditional Chinese medicine plays a significant role in the treatment of various diseases
and has attracted increasing attention for clinical applications. Vascular diseases affecting …

High glucose concentrations induce oxidative stress by inhibiting Nrf2 expression in rat Müller retinal cells in vitro

JS Albert-Garay, JR Riesgo-Escovar, R Salceda - Scientific reports, 2022 - nature.com
Diabetic retinopathy (DR) is a complication of diabetes. Several studies have implicated
oxidative stress as a fundamental factor in the progression of the disease. The nuclear factor …

Chromosome-scale assembly of the Dendrobium chrysotoxum genome enhances the understanding of orchid evolution

Y Zhang, GQ Zhang, D Zhang, XD Liu… - Horticulture …, 2021 - academic.oup.com
As one of the largest families of angiosperms, the Orchidaceae family is diverse.
Dendrobium represents the second largest genus of the Orchidaceae. However, an …

Advanced glycation end products in diabetic retinopathy and phytochemical therapy

Q Kang, H Dai, S Jiang, L Yu - Frontiers in Nutrition, 2022 - frontiersin.org
Advanced glycation end products (AGEs) are generated by the nonenzymatic glycation of
proteins or lipids. Diabetic retinopathy (DR) is one common complication in patients with …

[HTML][HTML] A review of traditional Chinese medicine on treatment of diabetic retinopathy and involved mechanisms

X Ai, P Yu, Y Hou, X Song, J Luo, N Li, X Lai… - Biomedicine & …, 2020 - Elsevier
As a common ocular complication and microangiopathy of type 2 diabetic mellitus, diabetic
retinopathy (DR) can lead to vision loss or even blindness in diabetic patients. At present …

Algae-Derived Natural Products in Diabetes and Its Complications—Current Advances and Future Prospects

L Pereira, A Valado - Life, 2023 - mdpi.com
Diabetes poses a significant global health challenge, necessitating innovative therapeutic
strategies. Natural products and their derivatives have emerged as promising candidates for …

DNA methylation in diabetic retinopathy: pathogenetic role and potential therapeutic targets

C Cai, C Meng, S He, C Gu, T Lhamo, D Draga, D Luo… - Cell & Bioscience, 2022 - Springer
Background Diabetic retinopathy (DR), a specific neuron-vascular complication of diabetes,
is a major cause of vision loss among middle-aged people worldwide, and the number of …