Proteases play causal roles in the malignant progression of human tumors. This review
centers on the roles in this process of cysteine cathepsins, ie, peptidases belonging to the …

The majority of breast cancer patients is treated with breast-conserving surgery (BCS)
combined with adjuvant radiation therapy. Up to 40% of patients has a tumor-positive …

The synthesis of four new oxorhenium (V) complexes containing the “3+ 1” mixed-ligand
donor set, ReO (SYS) X (where Y= S, py; X= Cl, Br), is described. All of the complexes tested …

Degradation components of basement membrane could be crucial for tumor invasion. A key
role in this process has been assigned to cysteine proteases, ie cathepsins and matrix …

AIM: The study is aimed to investigate if the sera and the tumor tissues of tongue cancer
patients demonstrate elevated cathepsin B activity during cancer progression and in vitro …

We studied the relation between the antipapain activity of cysteine proteinase inhibitors
(CPI) and immunohistochemical staining for cystatin C, using anti-chicken cystatin …

The emphasis of this book is on mechanisms and pathways regulating the expression and
actions of classical and novel tumor angiogenesis regulators. The contributors discuss their …

The activity of cysteine peptidases (cathepsins B and L) was estimated in homogenates of
tissues sampled during surgery from 60 patients operated due to colorectal tumors. The …

Background. The activity of autogenic proteolytic enzymes is regulated in vivo by autogenic
inhibitors. They play important roles in maintaining a balance in many processes in the …

AIM: To examine the effectiveness of human placental inhibitors, by injecting vitamin E to
rats with transplanted Morris-5123 hepatoma, on the expression of cathepsins B and L in …