Ribozymes, riboswitches and beyond: regulation of gene expression without proteins
A Serganov, DJ Patel - Nature Reviews Genetics, 2007 - nature.com
Although various functions of RNA are carried out in conjunction with proteins, some
catalytic RNAs, or ribozymes, which contribute to a range of cellular processes, require little …
catalytic RNAs, or ribozymes, which contribute to a range of cellular processes, require little …
The ubiquitous hammerhead ribozyme
The hammerhead ribozyme is a small catalytic RNA motif capable of endonucleolytic (self-)
cleavage. It is composed of a catalytic core of conserved nucleotides flanked by three …
cleavage. It is composed of a catalytic core of conserved nucleotides flanked by three …
Identification of hammerhead ribozymes in all domains of life reveals novel structural variations
J Perreault, Z Weinberg, A Roth… - PLoS computational …, 2011 - journals.plos.org
Hammerhead ribozymes are small self-cleaving RNAs that promote strand scission by
internal phosphoester transfer. Comparative sequence analysis was used to identify …
internal phosphoester transfer. Comparative sequence analysis was used to identify …
Searching genomes for ribozymes and riboswitches
New regulatory RNAs with complex structures have recently been discovered, among them
the first catalytic riboswitch, a gene-regulatory RNA sequence with catalytic activity. Here we …
the first catalytic riboswitch, a gene-regulatory RNA sequence with catalytic activity. Here we …
Metal ions: supporting actors in the playbook of small ribozymes
AE Johnson-Buck, SE McDowell, NG Walter - 2011 - books.rsc.org
Since the 1980s, several small RNA motifs capable of chemical catalysis have been
discovered. These small ribozymes, composed of between approximately 40 and 200 …
discovered. These small ribozymes, composed of between approximately 40 and 200 …
Kinetic Parameters of trans Scission by Extended HDV-like Ribozymes and the Prospect for the Discovery of Genomic trans-Cleaving RNAs
CHT Webb, A Lupták - Biochemistry, 2018 - ACS Publications
Hepatitis delta virus (HDV)-like ribozymes are self-cleaving catalytic RNAs with a
widespread distribution in nature and biological roles ranging from self-scission during …
widespread distribution in nature and biological roles ranging from self-scission during …
[PDF][PDF] The hammerhead ribozyme structure brought in line
R Przybilski, C Hammann - ChemBioChem, 2006 - scottlab.ucsc.edu
RNA catalysis seems to be considerably more wide spread than originally thought, with the
most prominent example being the ribosome, where RNA catalyses the peptidyl-transferase …
most prominent example being the ribosome, where RNA catalyses the peptidyl-transferase …
Helix-length compensation studies reveal the adaptability of the VS ribozyme architecture
J Lacroix-Labonte, N Girard, S Lemieux… - Nucleic acids …, 2012 - academic.oup.com
Compensatory mutations in RNA are generally regarded as those that maintain base
pairing, and their identification forms the basis of phylogenetic predictions of RNA secondary …
pairing, and their identification forms the basis of phylogenetic predictions of RNA secondary …
[PDF][PDF] RNA-Alignments und RNA-struktur in silico
A Wilm - Disseratation Heinrich-Heine-Universität …, 2006 - docserv.uni-duesseldorf.de
Man verzeihe mir, dass ich auf eine namentliche Erwähnung (auch ehemaliger) Mitarbeiter
des Instituts verzichte, die mir nicht nur fachlich, sondern auch persönlich zu Seite …
des Instituts verzichte, die mir nicht nur fachlich, sondern auch persönlich zu Seite …
[PDF][PDF] Biomolecular Correlation in Physical and Sequence Space
F Hoffgaard - 2011 - tuprints.ulb.tu-darmstadt.de
Investigating correlations is the key to understanding the nature of biological systems. In
general, correlations describe the relationship between data sets or specific characteristics …
general, correlations describe the relationship between data sets or specific characteristics …