Adult T-cell leukemia (ATL) is an aggressive hematologic malignancy caused by human T-
cell leukemia virus type I (HTLV-1). Tax, encoded by the HTLV-1 pX region, has been …

Human thioredoxin (TRX) was first identified in human T-cell leukemia virus type I (HTLV-I)-
positive T-cell lines and is associated with the pathophysiology of retroviral infections. TRX …

Common SNPs in the chromosome 17q12-q21 region alter the risk for asthma, type 1
diabetes, primary biliary cirrhosis, and Crohn disease. Previous reports by us and others …

The mechanism employed by DNA tumor viruses to inhibit p53-dependent transcription from
chromatin is poorly understood. Here, we use in vitro-reconstituted chromatin and UV …

Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic human retrovirus which
causes a lifelong infection. An estimated 5–10 million persons are infected with HTLV-1 …

Somatic cell reprogramming is accompanied by changes in lipid metabolism. While
attempting to dissect the molecular mechanisms of the lipid metabolic switch during …

Histone posttranslational modifications and chromatin dynamics are inextricably linked to
eukaryotic gene expression. Among the many modifications that have been characterized …

The viral Tax oncoprotein plays a key role in both Human T-cell lymphotropic virus type 1
(HTLV-1)-replication and HTLV-1-associated pathologies, notably adult T-cell leukemia. Tax …

Human T-cell leukemia virus type 1 (HTLV-I) has been implicated with the etiology of adult T-
cell leukemia (ATL) and certain other clinical disorders. Although the leukemogenic …

The human T cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T cell
leukemia/lymphoma. The multifunctional virally encoded oncoprotein Tax is responsible for …