A review of reverse vaccinology approaches for the development of vaccines against ticks and tick borne diseases

AE Lew-Tabor, MR Valle - Ticks and tick-borne diseases, 2016 - Elsevier
The field of reverse vaccinology developed as an outcome of the genome sequence
revolution. Following the introduction of live vaccinations in the western world by Edward …

Control of Lyme borreliosis and other Ixodes ricinus-borne diseases

H Sprong, T Azagi, D Hoornstra, AM Nijhof, S Knorr… - Parasites & vectors, 2018 - Springer
Lyme borreliosis (LB) and other Ixodes ricinus-borne diseases (TBDs) are diseases that
emerge from interactions of humans and domestic animals with infected ticks in nature …

Evaluation of effectiveness and safety of Subolesin anti-tick vaccine in Ugandan multi-site field trial

F Kabi, M Contreras, J Semakula, M Sánchez-Sánchez… - npj Vaccines, 2024 - nature.com
Vaccines are the most effective and sustainable intervention to control ticks and tick-borne
diseases (TBD). Using a personalized vaccine design based on regional tick genotypes, a …

Tick vaccines: current status and future directions

J de la Fuente, M Contreras - Expert review of vaccines, 2015 - Taylor & Francis
Ticks and tick-borne diseases are a growing problem affecting human and animal health
worldwide. Traditional control methods, based primarily on chemical acaricides, have …

Anaplasma marginale and Anaplasma phagocytophilum: Rickettsiales pathogens of veterinary and public health significance

FA Atif - Parasitology research, 2015 - Springer
Anaplasma marginale and Anaplasma phagocytophilum are the most important tick-borne
bacteria of veterinary and public health significance in the family Anaplasmataceae. The …

Vaccines against bovine babesiosis: where we are now and possible roads ahead

M Florin-Christensen, CE Suarez, AE Rodriguez… - Parasitology, 2014 - cambridge.org
Bovine babesiosis caused by the tick-transmitted haemoprotozoans Babesia bovis, Babesia
bigemina and Babesia divergens commonly results in substantial cattle morbidity and …

Cocktail anti-tick vaccines: The unforeseen constraints and approaches toward enhanced efficacies

C Ndawula Jr, AE Tabor - Vaccines, 2020 - mdpi.com
Ticks are second to mosquitoes as vectors of disease. Ticks affect livestock industries in
Asia, Africa and Australia at~ 1.13billionUSDperannum.Forinstance,80%oftheglobalcattlepopulationisatriskofinfestati …

Systematic review of ticks and tick-borne pathogens of small ruminants in Pakistan

A Ghafar, T Abbas, A Rehman, ZD Sandhu… - Pathogens, 2020 - mdpi.com
Ticks and tick-borne diseases (TTBDis) are a major constraint to the health and production
of small ruminants in Pakistan. Despite being the subject of intermittent studies over the past …

Oral vaccine formulation combining tick Subolesin with heat inactivated mycobacteria provides control of cross-species cattle tick infestations

PD Kasaija, M Contreras, F Kabi, S Mugerwa… - Vaccine, 2022 - Elsevier
Tick vaccines are necessary as part of a One Health approach for the control of tick
infestations and tick-borne diseases. Subolesin (SUB, also known as 4D8) is a tick …

Alpha proteobacteria of genus Anaplasma (Rickettsiales: Anaplasmataceae): Epidemiology and characteristics of Anaplasma species related to veterinary and public …

FA Atif - Parasitology, 2016 - cambridge.org
The Anaplasma species are important globally distributed tick-transmitted bacteria of
veterinary and public health importance. These pathogens, cause anaplasmosis in domestic …