[HTML][HTML] Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease
WY Wang, MS Tan, JT Yu, L Tan - Annals of translational medicine, 2015 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain, which is
characterized by the formation of extracellular amyloid plaques (or senile plaques) and …
characterized by the formation of extracellular amyloid plaques (or senile plaques) and …
The role of astrocytes in amyloid production and Alzheimer's disease
GR Frost, YM Li - Open biology, 2017 - royalsocietypublishing.org
Alzheimer's disease (AD) is marked by the presence of extracellular amyloid beta (Aβ)
plaques, intracellular neurofibrillary tangles (NFTs) and gliosis, activated glial cells, in the …
plaques, intracellular neurofibrillary tangles (NFTs) and gliosis, activated glial cells, in the …
Neuroinflammation in frontotemporal dementia
Frontotemporal dementia (FTD) refers to a group of progressive neurodegenerative
disorders with different pathological signatures, genetic variability and complex disease …
disorders with different pathological signatures, genetic variability and complex disease …
Recent developments in TSPO PET imaging as a biomarker of neuroinflammation in neurodegenerative disorders
Neuroinflammation is an inflammatory response in the brain and spinal cord, which can
involve the activation of microglia and astrocytes. It is a common feature of many central …
involve the activation of microglia and astrocytes. It is a common feature of many central …
A meta-analysis of cytokines in Alzheimer's disease
W Swardfager, K Lanctôt, L Rothenburg, A Wong… - Biological …, 2010 - Elsevier
BACKGROUND: Studies suggest that inflammation is involved in the neurodegenerative
cascade leading to Alzheimer's disease (AD) pathology and symptoms. This study sought to …
cascade leading to Alzheimer's disease (AD) pathology and symptoms. This study sought to …
Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview
F Brosseron, M Krauthausen, M Kummer… - Molecular …, 2014 - Springer
This article gives a comprehensive overview of cytokine and other inflammation associated
protein levels in plasma, serum and cerebrospinal fluid (CSF) of patients with Alzheimer's …
protein levels in plasma, serum and cerebrospinal fluid (CSF) of patients with Alzheimer's …
Serum antibodies to periodontal pathogens are a risk factor for Alzheimer's disease
BACKGROUND: Chronic inflammation in periodontal disease has been suggested as a
potential risk factor in Alzheimer's disease (AD). The purpose of this study was to examine …
potential risk factor in Alzheimer's disease (AD). The purpose of this study was to examine …
Imaging and fluid biomarkers in frontotemporal dementia
LH Meeter, LD Kaat, JD Rohrer… - Nature Reviews …, 2017 - nature.com
Frontotemporal dementia (FTD), the second most common type of presenile dementia, is a
heterogeneous neurodegenerative disease characterized by progressive behavioural …
heterogeneous neurodegenerative disease characterized by progressive behavioural …
Interleukin-6, a mental cytokine
A Spooren, K Kolmus, G Laureys, R Clinckers… - Brain research …, 2011 - Elsevier
Almost a quarter of a century ago, interleukin-6 (IL-6) was discovered as an inflammatory
cytokine involved in B cell differentiation. Today, IL-6 is recognized to be a highly versatile …
cytokine involved in B cell differentiation. Today, IL-6 is recognized to be a highly versatile …
[HTML][HTML] Massive gliosis induced by interleukin-6 suppresses Aβ deposition in vivo: evidence against inflammation as a driving force for amyloid deposition
P Chakrabarty, K Jansen-West, A Beccard… - The FASEB …, 2010 - ncbi.nlm.nih.gov
Proinflammatory stimuli, after amyloid β (Aβ) deposition, have been hypothesized to create a
self-reinforcing positive feedback loop that increases amyloidogenic processing of the Aβ …
self-reinforcing positive feedback loop that increases amyloidogenic processing of the Aβ …