[HTML][HTML] Tankyrases/β-catenin signaling pathway as an anti-proliferation and anti-metastatic target in hepatocarcinoma cell lines

J Huang, Q Qu, Y Guo, Y Xiang, D Feng - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Objective: The Wnt/β-catenin pathway is involved in the development of hepatocellular
carcinoma (HCC) and malignant events such as the epithelial-mesenchymal transition …

A Prospects Tool in Virus Research: Analyzing the Applications of Organoids in Virus Studies

Q Shen, Y Zhou, Y Zhou - Acta Tropica, 2024 - Elsevier
Organoids have emerged as a powerful tool for understanding the biology of the respiratory,
digestive, nervous as well as urinary system, investigating infections, and developing new …

Knockout of ClC-2 reveals critical functions of adherens junctions in colonic homeostasis and tumorigenicity

Y Jin, D Ibrahim, ST Magness… - American Journal of …, 2018 - journals.physiology.org
Adherens junctions (AJs), together with tight junctions (TJs), form an apical junctional
complex that regulates intestinal epithelial cell-to-cell adherence and barrier homeostasis …

Maternal transmission of an Igf2r domain 11: IGF2 binding mutant allele (Igf2rI1565A) results in partial lethality, overgrowth and intestinal adenoma progression

J Hughes, M Surakhy, S Can, M Ducker, N Davies… - Scientific Reports, 2019 - nature.com
The cation-independent mannose 6-phosphate/insulin-like growth factor-2 receptor
(M6P/IGF2R or IGF2R) traffics IGF2 and M6P ligands between pre-lysosomal and extra …

[HTML][HTML] CDH1 基因对小鼠胃类器官生长和E-caherin 表达的作用机制

邵伟, 余友杰, 夏海娜, 郑优优, 孙展杭, 严皓哲 - 世界华人消化杂志, 2024 - wjgnet.com
CDH1基因对小鼠胃类器官生长和E-caherin表达的作用机制 主页 简体中文 English 简体中文
登录 BPG Management System F6Publishing-Submit a Manuscript F6Publishing-世界华人消化 …

Id1, Spp1 and Pak3 are biomarkers of Smad4 and TGF-β1 dependency in conditional intestinal adenoma, organoids and colorectal cancer.

M Surakhy, J Matheson, D Barnes, E Carter, J Hughes… - bioRxiv, 2024 - biorxiv.org
The evolutionarily conserved TGF-β signalling pathway suppresses cell growth, yet loss of
function results in cancer phenotypes. Here, we evaluate loss of the TGF-β pathway signal …

Expression profile analysis of dermal papilla cells mRNA in response to WNT10B treatment

Q Zhou, Y Song, Q Zheng… - Experimental and …, 2020 - spandidos-publications.com
Dermal papilla cells (DPCs) are associated with the development of hair follicles (HFs) and
the regulation of the hair growth cycle. Previous studies have shown that Wnt family member …