Our review aims to examine the cellular and molecular mechanisms of cardiovascular
protection of green tea polyphenols, particularly epigallocatechin gallate (EGCG), which …

Eicosanoids are lipid signaling molecules derived from the oxidation of ω-6 fatty acids,
usually arachidonic acid. There are three major pathways, including the cyclooxygenase …

Liver cancer is a malignancy developed from underlying liver disease that encompasses
liver injury and metabolic disorders. The progression from these underlying liver disease to …

Increasing evidence has shown that reactive oxygen species (ROS) are important mediators
in liver ischemia/reperfusion injury (IRI). ROS include hydrogen peroxide (H2O2) …

Background Fulminant hepatic failure (FHF) lacks efficient therapies notwithstanding
increased comprehending of the inflammatory response and oxidative stress play crucial …

N-acetylcysteine (NAC) is an antioxidant and cytoprotective agent with scavenging action
against reactive oxygen species and inhibitory effects on pro-inflammatory cytokines. In a …

AIM: To investigate the effects of resveratrol on liver ischemia/reperfusion (I/R) injury in rats.
METHODS: A total of 40 male Sprague-Dawley rats weighing 240-290 g were randomized …

The aim of this study was to design and synthesize COX-1/COX-2 balanced inhibitors
incorporating the structural motifs of anti-inflammatory ascidian metabolites. We designed a …

In recent years, using genetic engineering and bioengineering techniques, Bifidobacterium
as a carrier to express specific functions of the protein or polypeptide, has become a new …

Abstract Cyclooxygenase-2 (COX-2) is a prostanoid-synthesizing enzyme that is critically
implicated in a variety of pathophysiological processes. Using a COX-2-deficient mouse …