A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of nanotherapeutics

RNL Lamptey, B Chaulagain, R Trivedi… - International journal of …, 2022 - mdpi.com
Neurodegenerative disorders are primarily characterized by neuron loss. The most common
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …

Intranasal nanotherapeutics for brain targeting and clinical studies in Parkinson's disease

P Saha, H Kathuria, MM Pandey - Journal of Controlled Release, 2023 - Elsevier
Parkinson's disease (PD) is the second leading neurodegenerative disease globally,
impacting the quality of life of millions of people. It is estimated that the treatment cost of PD …

Intranasal delivery of functionalized polymeric nanomaterials to the brain

S Zha, KL Wong, AH All - Advanced Healthcare Materials, 2022 - Wiley Online Library
Intravenous delivery of nanomaterials containing therapeutic agents and various cargos for
treating neurological disorders is often constrained by low delivery efficacy due to difficulties …

Genetic engineering for biohydrogen production from microalgae

J Zhang, D Xue, C Wang, D Fang, L Cao, C Gong - Iscience, 2023 - cell.com
The development of biohydrogen as an alternative energy source has had great economic
and environmental benefits. Hydrogen production from microalgae is considered a clean …

Self-assembled lecithin-chitosan nanoparticles improved rotigotine nose-to-brain delivery and brain targeting efficiency

P Saha, P Singh, H Kathuria, D Chitkara, MM Pandey - Pharmaceutics, 2023 - mdpi.com
Rotigotine (RTG) is a non-ergoline dopamine agonist and an approved drug for treating
Parkinson's disease. However, its clinical use is limited due to various problems, viz. poor …

Drug discovery and development targeting dementia

A Zagórska, A Czopek, M Fryc, A Jaromin, BJ Boyd - Pharmaceuticals, 2023 - mdpi.com
Dementia, most often associated with neurodegenerative diseases, affects millions of
people worldwide, predominantly the elderly. Unfortunately, no treatment is still available …

[HTML][HTML] Chitosan–An alternative drug delivery approach for neurodegenerative diseases

M Iyer, A Elangovan, R Sennimalai, HWS Babu… - Carbohydrate Polymer …, 2024 - Elsevier
Neurological disorders have become severe and dreadful issues around the globe that are
rarely directly mediated because of the blood-brain barrier (BBB). Despite the various …

Algal biorefinery culminating multiple value-added products: recent advances, emerging trends, opportunities, and challenges

K Yadav, S Vasistha, P Nawkarkar, S Kumar, MP Rai - 3 Biotech, 2022 - Springer
Algal biorefinery is rising as a prominent solution to economically fulfill the escalating global
requirement for nutrition, feed, fuel, and medicines. In recent years, scientific productiveness …

Rivastigmine-DHA ion-pair complex improved loading in hybrid nanoparticles for better amyloid inhibition and nose-to-brain targeting in Alzheimer's

NS Hinge, H Kathuria, MM Pandey - European Journal of Pharmaceutics …, 2023 - Elsevier
Rivastigmine hydrogen tartrate (RIV-HT) is given orally for Alzheimer's disease. However,
oral therapy shows low brain bioavailability, short half-life and gastrointestinal-mediated …

Fluorescence microscopic platforms imaging mitochondrial abnormalities in neurodegenerative diseases

Y Wang, P Wang, C Li - Advanced Drug Delivery Reviews, 2023 - Elsevier
Neurodegenerative diseases (NDs) are progressive disorders that cause the degeneration
of neurons. Mitochondrial dysfunction is a common symptom in NDs and plays a crucial role …