The power and potential of mitochondria transfer
N Borcherding, JR Brestoff - Nature, 2023 - nature.com
Mitochondria are believed to have originated through an ancient endosymbiotic process in
which proteobacteria were captured and co-opted for energy production and cellular …
which proteobacteria were captured and co-opted for energy production and cellular …
Mitochondrial transfer between cell crosstalk-an emerging role in mitochondrial quality control
Y Liu, T Fu, G Li, B Li, G Luo, N Li, Q Geng - Ageing Research Reviews, 2023 - Elsevier
Intercellular signaling and component conduction are essential for multicellular organisms'
homeostasis, and mitochondrial transcellular transport is a key example of such cellular …
homeostasis, and mitochondrial transcellular transport is a key example of such cellular …
Mitochondrial transplantation strategies in multifaceted induction of cancer cell death
A Cruz-Gregorio, AK Aranda-Rivera, I Amador-Martinez… - Life Sciences, 2023 - Elsevier
Otto Warburg hypothesized that some cancer cells reprogram their metabolism, favoring
glucose metabolism by anaerobic glycolysis (Warburg effect) instead of oxidative …
glucose metabolism by anaerobic glycolysis (Warburg effect) instead of oxidative …
[HTML][HTML] 'Slicing'glioblastoma drivers with the Swiss cheese model
The Swiss cheese model is used to assess risks and explain accidents in a variety of
industries. This model can be applied to dissect the homeostatic mechanisms whose …
industries. This model can be applied to dissect the homeostatic mechanisms whose …
[HTML][HTML] Mitochondrial transfer in tunneling nanotubes—a new target for cancer therapy
F Guan, X Wu, J Zhou, Y Lin, Y He, C Fan… - Journal of Experimental …, 2024 - Springer
A century ago, the Warburg effect was first proposed, revealing that cancer cells
predominantly rely on glycolysis during the process of tumorigenesis, even in the presence …
predominantly rely on glycolysis during the process of tumorigenesis, even in the presence …
[HTML][HTML] Preclinical Models and Technologies in Glioblastoma Research: Evolution, Current State, and Future Avenues
H Slika, Z Karimov, P Alimonti, T Abou-Mrad… - International journal of …, 2023 - mdpi.com
Glioblastoma is the most common malignant primary central nervous system tumor and one
of the most debilitating cancers. The prognosis of patients with glioblastoma remains poor …
of the most debilitating cancers. The prognosis of patients with glioblastoma remains poor …
[HTML][HTML] Targeting SIRT3 sensitizes glioblastoma to ferroptosis by promoting mitophagy and inhibiting SLC7A11
X Li, W Zhang, Z Xing, S Hu, G Zhang, T Wang… - Cell Death & …, 2024 - nature.com
Glioblastoma (GBM) cells require large amounts of iron for tumor growth and progression,
which makes these cells vulnerable to destruction via ferroptosis induction. Mitochondria are …
which makes these cells vulnerable to destruction via ferroptosis induction. Mitochondria are …
[HTML][HTML] Advances in mitophagy and mitochondrial apoptosis pathway-related drugs in glioblastoma treatment
W Li, X Xu - Frontiers in Pharmacology, 2023 - frontiersin.org
Glioblastoma (GBM) is the most common malignant tumor of the central nervous system
(CNS). It is a leading cause of death among patients with intracranial malignant tumors …
(CNS). It is a leading cause of death among patients with intracranial malignant tumors …
Piezotronic effect for in situ electrostimulation of neural stem cell therapy for nerve injury
W Wang, K Li, B Xia, W Ma, Y Li, J Zhang, L Wang… - Nano Energy, 2024 - Elsevier
Nerve injury threatens the health of humans and causes death and disability in adults
worldwide. The difficulty of recovery from nerve injury is that there is no newborn functional …
worldwide. The difficulty of recovery from nerve injury is that there is no newborn functional …
[HTML][HTML] Focusing on mitochondria in the brain: from biology to therapeutics
N Song, S Mei, X Wang, G Hu, M Lu - Translational Neurodegeneration, 2024 - Springer
Mitochondria have multiple functions such as supplying energy, regulating the redox status,
and producing proteins encoded by an independent genome. They are closely related to the …
and producing proteins encoded by an independent genome. They are closely related to the …