CXCR4-directed theranostics in oncology and inflammation
Given its prominent role in inflammation and cancer biology, the CXC motif chemokine
receptor 4 (CXCR4) has gained a lot of attention in the recent years. This review gives a …
receptor 4 (CXCR4) has gained a lot of attention in the recent years. This review gives a …
Machine learning and deep learning applications in multiple myeloma diagnosis, prognosis, and treatment selection
Simple Summary Multiple myeloma is a malignant neoplasm of plasma cells with complex
pathogenesis. With major progresses in multiple myeloma research, it is essential that we …
pathogenesis. With major progresses in multiple myeloma research, it is essential that we …
First-in-human experience of CXCR4-directed endoradiotherapy with 177Lu-and 90Y-labeled pentixather in advanced-stage multiple myeloma with extensive intra …
K Herrmann, M Schottelius, C Lapa, T Osl… - Journal of nuclear …, 2016 - Soc Nuclear Med
Chemokine receptor 4 (CXCR4) is a key factor for tumor growth and metastasis in several
types of human cancer. Based on promising experiences with a radiolabeled CXCR4 ligand …
types of human cancer. Based on promising experiences with a radiolabeled CXCR4 ligand …
Imaging of CXC motif chemokine receptor 4 expression in 690 patients with solid or hematologic neoplasms using 68Ga-pentixafor PET
In recent years, molecular imaging addressing the CXC motif chemokine receptor 4
(CXCR4) has increasingly been used in various clinical settings. Here, we aimed to assess …
(CXCR4) has increasingly been used in various clinical settings. Here, we aimed to assess …
[HTML][HTML] [68Ga] Pentixafor-PET/CT for imaging of chemokine receptor CXCR4 expression in multiple myeloma-Comparison to [18F] FDG and laboratory values
C Lapa, M Schreder, A Schirbel, S Samnick… - Theranostics, 2017 - ncbi.nlm.nih.gov
Abstract Chemokine (CXC motif) receptor 4 (CXCR4) is a key factor for tumor growth and
metastasis in several types of human cancer including multiple myeloma (MM). Proof-of …
metastasis in several types of human cancer including multiple myeloma (MM). Proof-of …
Automated Whole‐Body Bone Lesion Detection for Multiple Myeloma on 68Ga‐Pentixafor PET/CT Imaging Using Deep Learning Methods
The identification of bone lesions is crucial in the diagnostic assessment of multiple
myeloma (MM). 68Ga‐Pentixafor PET/CT can capture the abnormal molecular expression of …
myeloma (MM). 68Ga‐Pentixafor PET/CT can capture the abnormal molecular expression of …
Molecular imaging of the chemokine receptor CXCR4 after acute myocardial infarction
JT Thackeray, T Derlin, A Haghikia, LC Napp… - JACC: Cardiovascular …, 2015 - jacc.org
Objectives: An assay for molecular imaging of myocardial CXCR4 expression was
evaluated, in order to obtain mechanistic insights noninvasively based on quantitative …
evaluated, in order to obtain mechanistic insights noninvasively based on quantitative …
The beginning of the end for conventional RECIST—novel therapies require novel imaging approaches
M Gerwing, K Herrmann, A Helfen… - Nature reviews Clinical …, 2019 - nature.com
Owing to improvements in our understanding of the biological principles of tumour initiation
and progression, a wide variety of novel targeted therapies have been developed …
and progression, a wide variety of novel targeted therapies have been developed …
The aluminium-[18F]fluoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules
SJ Archibald, L Allott - EJNMMI radiopharmacy and chemistry, 2021 - Springer
Abstract The aluminium-[18F] fluoride ([18F] AlF) radiolabelling method combines the
favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal …
favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal …
Chemokine receptor-4 targeted PET/CT with 68Ga-Pentixafor in assessment of newly diagnosed multiple myeloma: comparison to 18F-FDG PET/CT
Q Pan, X Cao, Y Luo, J Li, J Feng, F Li - European journal of nuclear …, 2020 - Springer
Abstract Purpose 18 F-FDG PET/CT has some limitations in the evaluation of multiple
myeloma (MM). Since chemokine receptor-4 is overexpressed in MM, we perform a …
myeloma (MM). Since chemokine receptor-4 is overexpressed in MM, we perform a …