[HTML][HTML] Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation
H Hodges, C Fealko, N Soares - Translational pediatrics, 2020 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits
in social communication and the presence of restricted interests and repetitive behaviors …
in social communication and the presence of restricted interests and repetitive behaviors …
The contribution of environmental exposure to the etiology of autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental condition of heterogeneous
etiology. While it is widely recognized that genetic and environmental factors and their …
etiology. While it is widely recognized that genetic and environmental factors and their …
The contribution of de novo coding mutations to autism spectrum disorder
Whole exome sequencing has proven to be a powerful tool for understanding the genetic
architecture of human disease. Here we apply it to more than 2,500 simplex families, each …
architecture of human disease. Here we apply it to more than 2,500 simplex families, each …
A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex
The genetic etiology of autism spectrum disorder (ASD) is multifactorial, but how
combinations of genetic factors determine risk is unclear. In a large family sample, we show …
combinations of genetic factors determine risk is unclear. In a large family sample, we show …
Prenatal, perinatal, and postnatal factors associated with autism: A meta-analysis
C Wang, H Geng, W Liu, G Zhang - Medicine, 2017 - journals.lww.com
Background: The aim of this meta-analysis was to investigate the prenatal, perinatal, and
postnatal risk factors for children autism. Methods: PubMed, Embase, Web of Science were …
postnatal risk factors for children autism. Methods: PubMed, Embase, Web of Science were …
Rate of de novo mutations and the importance of father's age to disease risk
Mutations generate sequence diversity and provide a substrate for selection. The rate of de
novo mutations is therefore of major importance to evolution. Here we conduct a study of …
novo mutations is therefore of major importance to evolution. Here we conduct a study of …
[HTML][HTML] The global prevalence of autism spectrum disorder: A three-level meta-analysis
OI Talantseva, RS Romanova, EM Shurdova… - Frontiers in …, 2023 - frontiersin.org
Autism spectrum disorder (ASD) is one the most disabling developmental disorders,
imposing an extremely high economic burden. Obtaining as accurate prevalence estimates …
imposing an extremely high economic burden. Obtaining as accurate prevalence estimates …
Advanced parental age and autism risk in children: a systematic review and meta‐analysis
S Wu, F Wu, Y Ding, J Hou, J Bi… - Acta Psychiatrica …, 2017 - Wiley Online Library
Objective Advanced parental age has raised additional concern as a risk factor of autism.
We conducted a meta‐analysis of observational studies investigating the association …
We conducted a meta‐analysis of observational studies investigating the association …
Annual Research Review: The role of the environment in the developmental psychopathology of autism spectrum condition
Background Although autism spectrum condition (ASC) is strongly genetic in origin,
accumulating evidence points to the critical roles of various environmental influences on its …
accumulating evidence points to the critical roles of various environmental influences on its …
The age of fathers in the USA is rising: an analysis of 168 867 480 births from 1972 to 2015
ABSTRACT STUDY QUESTION How has the mean paternal age in the USA changed over
the past 4 decades? SUMMARY ANSWER The age at which men are fathering children in …
the past 4 decades? SUMMARY ANSWER The age at which men are fathering children in …