Cognitive and neuropsychiatric manifestations of COVID-19 and effects on elderly individuals with dementia

S Alonso-Lana, M Marquié, A Ruiz… - Frontiers in aging …, 2020 - frontiersin.org
The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread worldwide and has had …

The COVID-19 pandemic and Alzheimer's disease: mutual risks and mechanisms

F Chen, Y Chen, Y Wang, Q Ke, L Cui - Translational neurodegeneration, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19), which is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is a life-threatening disease, especially …

[HTML][HTML] The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice

EM Rhea, AF Logsdon, KM Hansen, LM Williams… - Nature …, 2021 - nature.com
It is unclear whether severe acute respiratory syndrome coronavirus 2, which causes
coronavirus disease 2019, can enter the brain. Severe acute respiratory syndrome …

Preexisting comorbidities predicting COVID-19 and mortality in the UK biobank community cohort

JL Atkins, JAH Masoli, J Delgado… - The Journals of …, 2020 - academic.oup.com
Background Hospitalized COVID-19 patients tend to be older and frequently have
hypertension, diabetes, or coronary heart disease, but whether these comorbidities are true …

APOE ε4 associates with increased risk of severe COVID-19, cerebral microhaemorrhages and post-COVID mental fatigue: a Finnish biobank, autopsy and clinical …

SN Kurki, J Kantonen, K Kaivola, L Hokkanen… - Acta neuropathologica …, 2021 - Springer
Apolipoprotein E ε4 allele (APOE4) has been shown to associate with increased
susceptibility to SARS-CoV-2 infection and COVID-19 mortality in some previous genetic …

Dementia is an age‐independent risk factor for severity and death in COVID‐19 inpatients

AC Tahira, S Verjovski‐Almeida… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction Dementia has been associated with COVID‐19 prevalence, but whether this
reflects higher infection, older age of patients, or disease severity remains unclear. Methods …

Heterogeneity in regional damage detected by neuroimaging and neuropathological studies in older adults with COVID-19: a cognitive-neuroscience systematic …

R Manca, M De Marco, PG Ince… - Frontiers in aging …, 2021 - frontiersin.org
Background: Other than its direct impact on cardiopulmonary health, Coronavirus Disease
2019 (COVID-19) infection affects additional body systems, especially in older adults …

[HTML][HTML] Mapping of SARS-CoV-2 brain invasion and histopathology in COVID-19 disease

GE Serrano, JE Walker, R Arce, MJ Glass, D Vargas… - MedRxiv, 2021 - ncbi.nlm.nih.gov
Abstract The coronavirus SARS-CoV-2 (SCV2) causes acute respiratory distress, termed
COVID-19 disease, with substantial morbidity and mortality. As SCV2 is related to previously …

The impact of dementia on the clinical outcome of COVID-19: a systematic review and meta-analysis

N Liu, J Sun, X Wang, M Zhao… - Journal of Alzheimer's …, 2020 - content.iospress.com
Background: The emergence of the coronavirus disease 2019 (COVID-19) has brought
large challenges to dementia patients. We reviewed the existing literature on COVID-19 to …

Genetic and epigenetic factors associated with increased severity of Covid‐19

Z Yildirim, OS Sahin, S Yazar… - Cell biology …, 2021 - Wiley Online Library
Since December 2019, a new form of severe acute respiratory syndrome (SARS) from a
novel strain of coronavirus (SARS coronavirus 2 [SARS‐CoV‐2]) has been spreading …