The relevance and insights on 1, 4-naphthoquinones as antimicrobial and antitumoral molecules: A systematic review

G Navarro-Tovar, S Vega-Rodríguez, E Leyva… - Pharmaceuticals, 2023 - mdpi.com
Natural product derivatives are essential in searching for compounds with important
chemical, biological, and medical applications. Naphthoquinones are secondary …

[HTML][HTML] An overview on the antibacterial properties of juglone, naphthazarin, plumbagin and lawsone derivatives and their metal complexes

C Majdi, V Duvauchelle, P Meffre… - Biomedicine & …, 2023 - Elsevier
Bacterial resistance development represents a serious threat to human health across the
globe and has become a very serious clinical problem for many classes of antibiotics …

Anti‐inflammatory Potential of 1, 4‐Naphthoquinone Acyl Thiourea Hybrids on Lipopolysaccharide‐Activated Mammalian Macrophages, and Their Acid Dissociation …

C Canatar, H Türkben, C Efeoglu, H Sari… - …, 2023 - Wiley Online Library
In this study, seven new and known 1, 4‐naphthoquinone acyl thiourea hybrids were
synthesized and their molecular structures were confirmed by various analytical methods …

Annulations involving p-benzoquinones: Stereoselective synthesis of fused-, spiro-and bridged molecules

S Das - New Journal of Chemistry, 2024 - pubs.rsc.org
Quinones are valuable structural motifs found in numerous natural products and
pharmaceuticals. In particular, p-benzoquinones are of great interest because of their ready …

2, 3-Dichloronaphthoquinone derivatives: Synthesis, antimicrobial activity, molecular modelling and ADMET studies

H Kolancılar, H Özcan, AŞ Yılmaz, AS Salan, A Ece - Bioorganic Chemistry, 2024 - Elsevier
In the present study, an intermediate namely 2-(3-bromopropylamino)-3-chloronaphthalene-
1, 4-dione was initially synthesized via the nucleophilic addition–elimination reaction …

Insight into the synergistic antibacterial mechanism of bio ZnO nanoparticles synthesized from Sophora japonica flower buds extract

F Yang, Y Li, B Mu, Q Wang, Y Song, A Wang - Inorganic Chemistry …, 2024 - Elsevier
Developing green nanotechnology to produce safe and powerful nano-antimicrobials has
become a hot direction for addressing the challenge of antibiotic resistance. In this study, to …

Exploring the anticancer and antibacterial potential of naphthoquinone derivatives: a comprehensive computational investigation

MH Meem, SB Yusuf, SS Al Abbad, S Rahman… - Frontiers in …, 2024 - frontiersin.org
This study investigates the potential of 2-(4-butylbenzyl)-3-hydroxynaphthalene-1, 4-dione
(11) and its 12 derivatives as anticancer and biofilm formation inhibitors for methicillin …

[HTML][HTML] Current status of 1, 4-Naphthoquinones and their derivatives for wound healing

P Kumari, V Singh, V Kant, M Ahuja - European Journal of Medicinal …, 2024 - Elsevier
Cutaneous wounds are a major healthcare concern affecting millions of people as they fail
to heal properly and can result in life threatening conditions and high economic loss. Wound …

The combinatorial applications of 1,4-naphthoquinone and tryptophan inhibit the biofilm formation of Staphylococcus aureus

P Paul, R Roy, S Das, S Sarkar, S Chatterjee… - Folia Microbiologica, 2023 - Springer
Microorganisms embedded within an extracellular polymeric matrix are known as biofilm.
The extensive use of antibiotics to overcome the biofilm-linked challenges has led to the …

In vitro antimicrobial, semisynthesis and in silico studies of 1, 2-naphthoquinone derivatives

A Dessie, S Degu, A Abebe, D Bisrat - Journal of Molecular Structure, 2025 - Elsevier
Naphthoquinones have emerged as a potential class of compounds for treating microbial
infections. In this study, our aim was to synthesize 1, 2-naphthoquinones (1, 2 NQs) starting …