Cyclodextrin complexes: Perspective from drug delivery and formulation
Cyclodextrins (CDs) have been widely investigated as a unique pharmaceutical excipient for
past few decades and is still explored for new applications. They are highly versatile …
past few decades and is still explored for new applications. They are highly versatile …
A systematic and robust assessment of hot-melt extrusion-based amorphous solid dispersions: Theoretical prediction to practical implementation
Amorphous solid dispersions (ASDs) have gained attention as a formulation strategy in
recent years, with the potential to improve the apparent solubility and, hence, the oral …
recent years, with the potential to improve the apparent solubility and, hence, the oral …
[HTML][HTML] Hot-melt extrusion in the pharmaceutical industry: toward filing a new drug application
MF Simões, RMA Pinto, S Simões - Drug Discovery Today, 2019 - Elsevier
The pharmaceutical development of amorphous solid dispersions (ASDs) by hot-melt
extrusion (HME) is briefly reviewed. A systematic step-by-step approach is presented, where …
extrusion (HME) is briefly reviewed. A systematic step-by-step approach is presented, where …
Hot-melt extrusion: Highlighting recent advances in pharmaceutical applications
Hot-melt extrusion (HME) has emerged as a pioneering manufacturing technology for
pharmaceutical industries, and the utilization is overgrowing due to its unit operation, cost …
pharmaceutical industries, and the utilization is overgrowing due to its unit operation, cost …
Direct cyclodextrin based powder extrusion 3D printing of budesonide loaded mini-tablets for the treatment of eosinophilic colitis in paediatric patients
M Pistone, GF Racaniello, R Rizzi, RM Iacobazzi… - International Journal of …, 2023 - Elsevier
The purpose of this study was to combine direct powder extrusion (DPE) 3D printing and
fluid bed coating techniques to create a budesonide (BD) loaded solid oral formulations for …
fluid bed coating techniques to create a budesonide (BD) loaded solid oral formulations for …
Antibacterial Effect and Possible Mechanism of Salicylic Acid Microcapsules against Escherichia coli and Staphylococcus aureus
X Song, R Li, Q Zhang, S He, Y Wang - International Journal of …, 2022 - mdpi.com
Microcapsules serve as a feasible formulation to load phenolic substances such as salicylic
acid, a natural and safe antimicrobial agent. However, the antibacterial efficacy of salicylic …
acid, a natural and safe antimicrobial agent. However, the antibacterial efficacy of salicylic …
Recent advances in the pharmaceutical and biomedical applications of cyclodextrin-capped gold nanoparticles
AAH Abdellatif, F Ahmed, AM Mohammed… - International Journal …, 2023 - Taylor & Francis
The real problem in pharmaceutical preparation is drugs' poor aqueous solubility, low
permeability through biological membranes, and short biological t1/2. Conventional drug …
permeability through biological membranes, and short biological t1/2. Conventional drug …
Mucoadhesive buccal films for treatment of xerostomia prepared by coupling HME and 3D printing technologies
RM Elkanayati, WG Chambliss, S Omari… - Journal of Drug Delivery …, 2022 - Elsevier
Polyethylene oxide-based muco-adhesive buccal films containing adipic acid active
pharmaceutical ingredient (API) and xylitol were developed using hot-melt extrusion (HME) …
pharmaceutical ingredient (API) and xylitol were developed using hot-melt extrusion (HME) …
Predictive models of FDM 3D printing using experimental design based on pharmaceutical requirements for tablet production
The present study aimed to analyze how the printing process affects the final state of a
printed pharmaceutical product and to establish prediction models for post-printing …
printed pharmaceutical product and to establish prediction models for post-printing …
Hot-melt extrusion: from theory to application in pharmaceutical formulation—where are we now?
Hot-melt extrusion (HME) is a globally recognized, robust, effective technology that
enhances the bioavailability of poorly soluble active pharmaceutical ingredients and offers …
enhances the bioavailability of poorly soluble active pharmaceutical ingredients and offers …